Evidence map›Paper›PMID 30477216›Full record

ReviewJournal of clinical medicine2018

Interstitial Lung Disease and Pulmonary Fibrosis: A Practical Approach for General Medicine Physicians with Focus on the Medical History.

Or Kalchiem-Dekel, Jeffrey R Galvin, Allen P Burke, Sergei P Atamas, Nevins W Todd

Abstract readReview
In one paragraph

Review in Journal of clinical medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  9. The intersection of liver cirrhosis and pulmonary fibrosis.Journal of translational medicine · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Or Kalchiem-DekelDepartment of Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA. orkalchiemdekel@umm.edu.ORCID 0000-0001-9856-627X
Jeffrey R GalvinDepartment of Radiology and Nuclear Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA. jgalvin@umm.edu.
Allen P BurkeDepartment of Pathology, University of Maryland School of Medicine, Baltimore, MD 21201, USA. aburke@umm.edu.
Sergei P AtamasDepartment of Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA. satamas@som.umaryland.edu.
Nevins W ToddDepartment of Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA. ntodd@som.umaryland.edu.

Funding

The Central Role of IL-33 in Immune-Mediated ScarringI01BX002499 · VA · BALTIMORE VA MEDICAL CENTER · PI LUZINA, IRINA G. · 2015 to 2020
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BLRD VA I01 BX002499National Institutes of Health R01HL126897U.S. Department of Veterans Affairs I01BX002499U.S. Department of Veterans Affairs I01CX000101
6 · The paper itself

Abstract

Interstitial lung disease (ILD) and pulmonary fibrosis comprise a wide array of inflammatory and fibrotic lung diseases which are often confusing to general medicine and pulmonary physicians alike. In addition to the myriad of clinical and radiologic nomenclature used in ILD, histopathologic descriptors may be particularly confusing, and are often extrapolated to radiologic imaging patterns which may further add to the confusion. We propose that rather than focusing on precise histologic findings, focus should be on identifying an accurate etiology of ILD through a comprehensive and detailed medical history. Histopathologic patterns from lung biopsy should not be dismissed, but are often nonspecific, and overall treatment strategy and prognosis are likely to be determined more by the specific etiology of ILD rather than any particular histologic pattern. In this review, we outline a practical approach to common ILDs, highlight important aspects in obtaining an exposure history, clarify terminology and nomenclature, and discuss six common subgroups of ILD likely to be encountered by general medicine physicians in the inpatient or outpatient setting: Smoking-related, hypersensitivity pneumonitis, connective tissue disease-related, occupation-related, medication-induced, and idiopathic pulmonary fibrosis. Accurate diagnosis of these forms of ILD does require supplementing the medical history with results of the physical examination, autoimmune serologic testing, and chest radiographic imaging, but the importance of a comprehensive environmental, avocational, occupational, and medication-use history cannot be overstated and is likely the single most important factor responsible for achieving the best possible outcomes for patients.

Indexed as

autoimmunehypersensitivityidiopathic pulmonary fibrosisoccupationsmoking

Identifiers

PMID30477216
PMCPMC6306719

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.