Evidence map›Paper›PMID 30477209›Full record

ArticleHealthcare (Basel, Switzerland)2018

Assessment of the Impact of Deformable Registration of Diagnostic MRI to Planning CT on GTV Delineation for Radiotherapy for Oropharyngeal Carcinoma in Routine Clinical Practice.

Alice Taylor, Mehmet Sen, Robin J D Prestwich

Abstract read
In one paragraph

Article in Healthcare (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Alice TaylorSchool of Medicine, Worsley Building, University of Leeds, Leeds LS2 9JT, UK. um13a2t@leeds.ac.uk.
Mehmet SenDepartment of Clinical Oncology, St. James's University Hospital, Leeds Cancer Centre, Beckett Street, Leeds LS9 7TF, UK. mehmet.sen@nhs.net.ORCID 0000-0002-7005-8246
Robin J D PrestwichDepartment of Clinical Oncology, St. James's University Hospital, Leeds Cancer Centre, Beckett Street, Leeds LS9 7TF, UK. Robin.Prestwich@nhs.net.ORCID 0000-0002-7872-2826

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAim of study was to assess impact of deformable registration of diagnostic MRI to planning CT upon gross tumour volume (GTV) delineation of oropharyngeal carcinoma in routine practice.

methods22 consecutive patients with oropharyngeal squamous cell carcinoma treated with definitive (chemo)radiotherapy between 2015 and 2016, for whom primary GTV delineation had been performed by a single radiation oncologist using deformable registration of diagnostic MRI to planning CT, were identified. Separate GTVs were delineated as part of routine clinical practice (all diagnostic imaging available side-by-side for each delineation) using: CT (GTV

resultsMedian GTV volumes were 13.7 cm³ (range 3.5⁻41.7), 15.9 cm³ (range 1.6⁻38.3), 19.9 cm³ (range 5.5⁻44.5) for GTV

conclusionsThese data suggest a complementary role of MRI to CT to reduce the risk of geographical misses, although they highlight the potential for larger target volumes and hence toxicity.

Indexed as

deformable image registrationgross tumour volumemagnetic resonance imagingoropharyngeal squamous cell carcinomaradiotherapy

Identifiers

PMID30477209
PMCPMC6316469

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.