Evidence map›Paper›PMID 30476911›Full record

ArticleNeuroepidemiology2019

Cognitive Function and Impairment in Older, Rural South African Adults: Evidence from "Health and Aging in Africa: A Longitudinal Study of an INDEPTH Community in Rural South Africa".

Lindsay C Kobayashi, Farrah J Mateen, Livia Montana, Ryan G Wagner, Kathleen Kahn, Stephen M Tollman, Lisa F Berkman

Abstract read
In one paragraph

Article in Neuroepidemiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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  14. Risk factors for mild cognitive impairment among older adults in a hospital in southern Nigeria.African journal of primary health care & family medicine · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lindsay C KobayashiLombardi Comprehensive Cancer Center, Georgetown University, Washington, District of Columbia, USA.
Farrah J MateenDepartment of Neurology, Massachusetts General Hospital, Boston, Massachusetts, USA.
Livia MontanaHarvard Center for Population and Development Studies, Harvard T.H. Chan School of Public Health, Cambridge, Massachusetts, USA.
Ryan G WagnerMRC/Wits Rural Public Health and Health Transitions Research Unit (Agincourt), School of Public Health, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Kathleen KahnHarvard Center for Population and Development Studies, Harvard T.H. Chan School of Public Health, Cambridge, Massachusetts, USA.
Stephen M TollmanHarvard Center for Population and Development Studies, Harvard T.H. Chan School of Public Health, Cambridge, Massachusetts, USA.
Lisa F BerkmanHarvard Center for Population and Development Studies, Harvard T.H. Chan School of Public Health, Cambridge, Massachusetts, USA, lberkman@hsph.harvard.edu.

Funding

SOCIAL AND ECONOMIC PREDICTORS OF PHYSICAL AND COGNITIVE FUNCTIONP01AG041710 · NIA · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI LISA F BERKMAN, THOMAS A GAZIANO · 2013 to 2026
$37.3M
Shared Core: Biobanking, Bioinformatics and Data ManagementU54HG006938 · NHGRI · WITS HEALTH CONSORTIUM (PTY), LTD · PI RAMSAY, MICHELE MICHELE · 2012 to 2022
$12.2M
The Center for the Global Demography of AgingP30AG024409 · NIA · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI BLOOM, DAVID E · 2004 to 2019
$7.9M
An Innovative Language Controlled Tablet-Based Cognitive Test: Harmonizing Dementia Screening across High and Low Literacy CountriesR01AG051144 · NIA · HARVARD SCHOOL OF PUBLIC HEALTH · PI BERKMAN, LISA F · 2015 to 2016
$764k
NHGRI NIH HHS U54 HG006938NIA NIH HHS P01 AG041710NIA NIH HHS P30 AG024409NIA NIH HHS R01 AG051144Wellcome Trust
6 · The paper itself

Abstract

BACKGROUND/

aimsWe aimed to estimate the prevalence of cognitive impairment, and the sociodemographic and comorbid predictors of cognitive function among older, rural South African adults.

methodsData were from a population-based study of 5,059 adults aged ≥40 years in rural South Africa in 2015. Cognitive impairment was defined as scoring ≤1.5 SDs below the mean composite time orientation and memory score, or requiring a proxy interview with "fair" or "poor" proxy-reported memory. Multiple linear regression estimated the sociodemographic and comorbid predictors of cognitive score, with multiplicative statistical interactions between each of age and sex with education.

resultsCognitive impairment increased with age, from 2% of those aged 40-44 (11/516) to 24% of those aged ≥75 years (214/899). The independent predictors of lower cognitive score were being older, female, unmarried, not working, having low education, low household wealth, and a history of cardiovascular conditions. Education modified the negative associations between female sex, older age, and cognitive function score.

conclusionsThe prevalence of cognitive impairment increased with age and is comparable to rates of dementia reported in other sub-Saharan African countries. Age and sex differences in cognitive function scores were minimized as education increased, potentially reflecting the power of even poor-quality education to improve cognitive reserve.

Indexed as

AdultAgedAged, 80 and overAge FactorsCognitionCognition DisordersCognitive DysfunctionCross-Sectional StudiesEducational StatusFemaleHumansMaleMiddle AgedPrevalenceRisk FactorsRural PopulationAfricaAge factorsCognitive functionCognitive impairmentCross-sectional studiesEducationEpidemiologyPrevalenceSexSociodemographic characteristics

Identifiers

PMID30476911
PMCPMC6531856

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.