Evidence map›Paper›PMID 30476356›Full record

ArticleAddiction (Abingdon, England)2019

How competent are people who use opioids at responding to overdoses? Qualitative analyses of actions and decisions taken during overdose emergencies.

Joanne Neale, Caral Brown, Aimee N C Campbell, Jermaine D Jones, Verena E Metz, John Strang, Sandra D Comer

Open access · greenAbstract read
In one paragraph

Article in Addiction (Abingdon, England), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
7.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it, 55 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 3 countries.

Joanne NealeNational Addiction Centre, King's College London, London, UK.ORCID 0000-0003-1502-5983
Caral BrownNational Addiction Centre, King's College London, London, UK.
Aimee N C CampbellDivision on Substance Use Disorders, Columbia University Medical Center and New York State Psychiatric Institute, New York, USA.
Jermaine D JonesDivision on Substance Use Disorders, Columbia University Medical Center and New York State Psychiatric Institute, New York, USA.
Verena E MetzDivision on Substance Use Disorders, Columbia University Medical Center and New York State Psychiatric Institute, New York, USA.ORCID 0000-0002-9720-424X
John StrangNational Addiction Centre, King's College London, London, UK.ORCID 0000-0002-5413-2725
Sandra D ComerDivision on Substance Use Disorders, Columbia University Medical Center and New York State Psychiatric Institute, New York, USA.
Columbia University Irving Medical Center · USKing's College London · GB

Funding

Risk and Benefits of Overdose Education and Naloxone Prescribing to Heroin UsersR01DA035207 · NIDA · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI COMER, SANDRA D · 2014 to 2018
$2.7M
NIDA NIH HHS R01 DA035207
6 · The paper itself

Abstract

BACKGROUND AND

aimsProviding take-home naloxone (THN) to people who use opioids is an increasingly common strategy for reversing opioid overdose. However, implementation is hindered by doubts regarding the ability of people who use opioids to administer naloxone and respond appropriately to overdoses. We aimed to increase understanding of the competencies required and demonstrated by opioid users who had recently participated in a THN programme and were subsequently confronted with an overdose emergency.

designQualitative study designed to supplement findings from a randomized controlled trial of overdose education and naloxone distribution. Interviews were audio-recorded, transcribed, systematically coded and analysed via Iterative Categorization.

settingNew York City, USA.

participantsThirty-nine people who used opioids (32 men, 7 women; aged 22-58 years).

interventionTrial participants received brief or extended overdose training and injectable or nasal naloxone. MEASUREMENTS: The systematic coding frame comprised deductive codes based on the topic guide and more inductive codes emerging from the data.

findingsIn 38 of 39 cases the victim was successfully resuscitated; the outcome of one overdose intervention was unknown. Analyses revealed five core overdose response 'tasks': (1) overdose identification; (2) mobilizing support; (3) following basic first aid instructions; (4) naloxone administration; and (5) post-resuscitation management. These tasks comprised actions and decisions that were themselves affected by diverse cognitive, emotional, experiential, interpersonal and social factors over which lay responders often had little control. Despite this, participants demonstrated high levels of competency. They had acquired new skills and knowledge through training and brought critical 'insider' understanding to overdose events and the resuscitation actions which they applied.

conclusionsPeople who use opioids can be trained to respond appropriately to opioid overdoses and thus to save their peers' lives. Overdose response requires both practical competency (e.g. skills and knowledge in administering basic first aid and naloxone) and social competency (e.g. willingness to help others, having the confidence to be authoritative and make decisions, communicating effectively and demonstrating compassion and care to victims post-resuscitation).

Indexed as

Emergency TreatmentAdultAnalgesics, OpioidDrug OverdoseFemaleHumansMaleMiddle AgedNaloxoneNarcotic AntagonistsNew York CityProgram EvaluationQualitative ResearchYoung AdultAnalgesics, OpioidNaloxoneNarcotic AntagonistsCardiopulmonary resuscitationcompetencynaloxoneover-antagonismoverdosequalitativetake-home naloxonetraining

Identifiers

PMID30476356
PMCPMC6411430
OpenAlexW2903129964

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.