ArticleJournal of experimental botany2019
Arabidopsis ADF5 promotes stomatal closure by regulating actin cytoskeleton remodeling in response to ABA and drought stress.
Article in Journal of experimental botany, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers.
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58 citing papers in PubMed, 115 citations in OpenAlex.
- Genomic and genetic dissection underlying seedling drought resilience in oats.Nature communications · 2026Article
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- Nuclear Entanglement: New Insights Into the Role of Cytoskeleton and Nucleoskeleton in Plant Nuclear Function.Cytoskeleton (Hoboken, N.J.) · 2026Review
- Systematic Analysis of theLife (Basel, Switzerland) · 2026Article
- Review
- FIMBRIN2 Regulates ABA-Induced Stomatal Closure by Promoting Microfilament Bundling and Turnover in Arabidopsis Guard Cells.Plant direct · 2026Article
- The RCAR12-CAP1-OST1 module controls ABA-mediated stomatal closure in Arabidopsis.PLoS genetics · 2026Article
- Cytoskeletal control of development and environmental adaptation in plants.Science China. Life sciences · 2026Review
- Genome-wide identification and stress-responsive expression analysis of the Actin-Depolymerizing Factor (ADF) gene family in Avena sativa L.BMC plant biology · 2026Article
- The ADF4-RCAR12 module regulates ABA-mediated drought tolerance inFrontiers in plant science · 2026Article
- Global analysis of soybean bZIP gene family under stress and identification of salt-stress-responsive candidate genes.Frontiers in plant science · 2026Article
- Dancing molecules: group A bZIPs and PEBPs at the heart of plant development and stress responses.Journal of experimental botany · 2025Review
- Genome-wide characterization and expression profiling of FIMBRIN gene family members in response to abiotic stress in Medicago sativa.BMC plant biology · 2025Article
- Early transcriptomic changes in cucumber and maize roots in response to FePOScientific reports · 2025Article
- Genome-Wide Analysis of bZIP Transcription Factors and Expression Patterns in Response to Salt and Drought Stress inInternational journal of molecular sciences · 2025Article
- Genome-wide identification, characterization and expression profiles of FORMIN gene family in cotton (Gossypium Raimondii L.).BMC genomic data · 2024Article
- MYB52 negatively regulates ADF9-meditated actin filament bundling in Arabidopsis pavement cell morphogenesis.Journal of integrative plant biology · 2024Article
- Arabidopsis Actin-Binding Protein WLIM2A Links PAMP-Triggered Immunity and Cytoskeleton Organization.International journal of molecular sciences · 2024Article
- Investigating the Role of Known Arabidopsis Iron Genes in a Stress Resilient Soybean Line.International journal of molecular sciences · 2024Article
- Transcriptome analysis and characteristics of drought resistance related genes in four varieties of foxtail millet [Heliyon · 2024Article
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Authors and funding
13 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Stomatal movement plays an essential role in plant responses to drought stress, and the actin cytoskeleton and abscisic acid (ABA) are two important components of this process. Little is known about the mechanism underlying actin cytoskeleton remodeling and the dynamic changes occurring during stomatal movement in response to drought stress/ABA signaling. Actin-depolymerizing factors (ADFs) are conserved actin severing/depolymerizing proteins in eukaryotes, and in angiosperms ADFs have evolved actin-bundling activity. Here, we reveal that the transcriptional expression of neofunctionalized Arabidopsis ADF5 was induced by drought stress and ABA treatment. Furthermore, we demonstrated that ADF5 loss-of-function mutations increased water loss from detached leaves, reduced plant survival rates after drought stress, and delayed stomatal closure by regulating actin cytoskeleton remodeling via its F-actin-bundling activity. Biochemical assays revealed that an ABF/AREB transcription factor, DPBF3, could bind to the ADF5 promoter and activate its transcription via the ABA-responsive element core motif ACGT/C. Taken together, our findings indicate that ADF5 participates in drought stress by regulating stomatal closure, and may also serve as a potential downstream target of the drought stress/ABA signaling pathway via members of the ABF/AREB transcription factors family.
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