Evidence map›Paper›PMID 30476170›Full record

ArticleNephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association2019

Long-term blood pressure monitoring by office and 24-h ambulatory blood pressure in renal transplant patients: a longitudinal study.

Francesca Mallamaci, Rocco Tripepi, Graziella D'Arrigo, Gaetana Porto, Maria Carmela Versace, Carmela Marino, Maria Cristina Sanguedolce, Alessandra Testa, Giovanni Tripepi, Carmine Zoccali

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Article in Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. A European Renal Association (ERA) synopsis for nephrology practice of the 2023 European Society of Hypertension (ESH) Guidelines for the Management of Arterial Hypertension.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2024
    Guideline
  2. Article
  3. Review
  4. Article
  5. Article
  6. Adverse Drug Events after Kidney Transplantation.Journal of personalized medicine · 2023
    Review
  7. Hypertension in kidney transplant recipients.World journal of transplantation · 2022
    Review
  8. Article
  9. Review
  10. Article
  11. Use of ambulatory blood pressure monitoring in kidney transplant recipients.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2019
    Article
  12. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Francesca MallamaciNephrology, Dialysis and Transplantation Unit, Ospedali Riuniti, Reggio Calabria, Italy.
Rocco TripepiCNR-IFC (National Research Centre, Institute of Clinical Physiology), Clinical Epidemiology of Renal Diseases and Hypertension Unit, Reggio Calabria, Italy.
Graziella D'ArrigoCNR-IFC (National Research Centre, Institute of Clinical Physiology), Clinical Epidemiology of Renal Diseases and Hypertension Unit, Reggio Calabria, Italy.
Gaetana PortoCNR-IFC (National Research Centre, Institute of Clinical Physiology), Clinical Epidemiology of Renal Diseases and Hypertension Unit, Reggio Calabria, Italy.
Maria Carmela VersaceCNR-IFC (National Research Centre, Institute of Clinical Physiology), Clinical Epidemiology of Renal Diseases and Hypertension Unit, Reggio Calabria, Italy.
Carmela MarinoCNR-IFC (National Research Centre, Institute of Clinical Physiology), Clinical Epidemiology of Renal Diseases and Hypertension Unit, Reggio Calabria, Italy.
Maria Cristina SanguedolceCNR-IFC (National Research Centre, Institute of Clinical Physiology), Clinical Epidemiology of Renal Diseases and Hypertension Unit, Reggio Calabria, Italy.
Alessandra TestaCNR-IFC (National Research Centre, Institute of Clinical Physiology), Clinical Epidemiology of Renal Diseases and Hypertension Unit, Reggio Calabria, Italy.
Giovanni TripepiCNR-IFC (National Research Centre, Institute of Clinical Physiology), Clinical Epidemiology of Renal Diseases and Hypertension Unit, Reggio Calabria, Italy.
Carmine ZoccaliCNR-IFC (National Research Centre, Institute of Clinical Physiology), Clinical Epidemiology of Renal Diseases and Hypertension Unit, Reggio Calabria, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRenal transplant patients have a high prevalence of nocturnal hypertension, and hypertension misclassification by office blood pressure (BP) is quite common in these patients. The potential impact of hypertension misclassification by office BP on hypertension management in this population has never been analysed.

methodsWe performed a longitudinal study in a cohort of 260 clinically stable renal transplant patients. In all, 785 paired office and 24-h ambulatory blood pressure monitoring (24-hABPM) measurements over a median follow-up of 3.9 years were available in the whole cohort.

resultsA total of 74% of patients had nocturnal hypertension (>120/70 mmHg). Average office BP and 24-hABPM remained quite stable over follow-up, as did the prevalence of nocturnal hypertension, which was 77% at the last observation. However, the global agreement between office BP and average 24 h, daytime and night-time BP was unsatisfactory (k-statistics 0.10-0.26). In 193 visits (25% of all visits) where office BP indicated the need of antihypertensive therapy institution or modification (BP >140/90 mmHg), 24-hABPM was actually normal (<130/80 mmHg), while in 94 visits (12%), 24-hABPM was in the hypertensive range while office BP was normal. Overall, in 37% of visits, office BP provided misleading therapeutic indications.

conclusionsHypertension misclassification by office BP is a common phenomenon in stable renal transplant patients on long-term follow-up. Office BP may lead to inappropriate therapeutic decisions in over one-third of follow-up visits in these patients.

Indexed as

Kidney TransplantationBlood PressureBlood Pressure DeterminationBlood Pressure Monitoring, AmbulatoryFemaleHumansHypertensionItalyLongitudinal StudiesMaleMiddle AgedPrevalenceTime Factorsambulatory blood pressure monitoringcardiovascularhypertensionkidney transplantation

Identifiers

PMID30476170

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.