Evidence map›Paper›PMID 30475308›Full record

ArticleJournal of occupational and environmental medicine2019

Vascular Aging Is Accelerated in Flight Attendants With Occupational Secondhand Smoke Exposure.

Janet Wei, Chrisandra Shufelt, Eveline Oestreicher Stock, Claire Mills, Shivani Dhawan, Riya Jacob, Tina Torbati, Galen Cook-Wiens, Neal Benowitz, Peyton Jacob and 3 more

Abstract read
In one paragraph

Article in Journal of occupational and environmental medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 2 countries.

Janet WeiBarbra Streisand Women's Heart Center, Cedars-Sinai Heart Institute (Drs Wei, Shufelt, Ms Dhawan, Ms Torbati, Dr Bairey Merz); Flight Attendant Medical Research Institute (FAMRI) Bland Lane Center of Excellence on Second Hand Smoke (Dr Oestreicher Stock, Ms Jacob, Dr Benowitz, Mr Jacob, Dr Redberg); Division of Cardiology, Center of Excellence in Vascular Research at the San Francisco General Hospital (Ms Mills, Dr Ganz); Biostatistics and Bioinformatics Core (Mr Cook-Wiens), Cedars-Sinai Medical Center, Los Angeles; University of California, San Francisco Center for Tobacco Control Research and Education Tobacco Centers of Regulatory Science (TCORS) (Dr Ganz); and Division of Cardiology, Department of Medicine (Drs Oestreicher Stock, Redberg), University of California, San Francisco, San Francisco, California.
Chrisandra Shufelt
Eveline Oestreicher Stock
Claire Mills
Shivani Dhawan
Riya Jacob
Tina Torbati
Galen Cook-Wiens
Neal Benowitz
Peyton Jacob
Peter Ganz
Cathleen Noel Bairey Merz
Rita Redberg
Cedars-Sinai Medical Center · US

Funding

Research Support CoreP30DA012393 · NIDA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI JACOB, PEYTON · 1999 to 2024
$17.1M
Atherosclerosis, Immune Mediated Inflammation and Hypoestrogenemia in Young WomenK23HL127262 · NHLBI · CEDARS-SINAI MEDICAL CENTER · PI SHUFELT, CHRISANDRA LEE · 2016 to 2020
$988k
Liquid Chromatograph-Triple Quadrupole Mass SpectrometerS10RR026437 · NCRR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI JACOB, PEYTON · 2010 to 2010
$448k
NCRR NIH HHS S10 RR026437NHLBI NIH HHS K23 HL127262NIDA NIH HHS P30 DA012393
6 · The paper itself

Abstract

objectiveTo determine whether early vascular aging may be present in flight attendants with remote in-cabin secondhand smoke (SHS) exposure.

methodsTwenty-six flight attendants with a history of in-cabin SHS exposure prior to the airline smoking bans were recruited. Pulse wave analysis, peripheral arterial tonometry, and brachial artery reactivity testing evaluated their arterial compliance and endothelial function.

resultsFlight attendants with remote in-cabin SHS exposure have normal blood pressure, pulse wave velocity, and reactive hyperemia index, but abnormal pulse pressure, augmentation index, flow-mediated dilation, and hyperemic mean flow ratio.

conclusionThese preliminary findings suggest that flight attendants with remote in-cabin SHS exposure have preclinical signs of accelerated vascular aging and raise new questions about the relationship between remote SHS exposure and vascular health.

Indexed as

AircraftVascular StiffnessAerospace MedicineAgedBlood VesselsFemaleHumansMaleMiddle AgedOccupational ExposurePulse Wave AnalysisSurveys and QuestionnairesTobacco Smoke PollutionTobacco Smoke Pollution

Identifiers

PMID30475308
PMCPMC6698135
OpenAlexW2901492878

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.