Evidence map›Paper›PMID 30474937›Full record

ArticleStem cells translational medicine2019

Role of CXCR2 in the Ac-PGP-Induced Mobilization of Circulating Angiogenic Cells and its Therapeutic Implications.

Yang Woo Kwon, Seung Jun Lee, Soon Chul Heo, Tae Wook Lee, Gyu Tae Park, Jung Won Yoon, Seung-Chul Kim, Ho Jin Shin, Sang Chul Lee, Jae Ho Kim

Open access · goldAbstract read
In one paragraph

Article in Stem cells translational medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Increasing the Therapeutic Potential of Stem Cell Therapies for Critical Limb Ischemia.HSOA journal of stem cells research, development & therapy · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Yang Woo KwonDepartment of Physiology, Pusan National University School of Medicine, Yangsan, Republic of Korea.
Seung Jun LeeDepartment of Orthopaedic Surgery, Pusan National University School of Medicine, Yangsan, Republic of Korea.
Soon Chul HeoDepartment of Physiology, Pusan National University School of Medicine, Yangsan, Republic of Korea.
Tae Wook LeeDepartment of Physiology, Pusan National University School of Medicine, Yangsan, Republic of Korea.
Gyu Tae ParkDepartment of Physiology, Pusan National University School of Medicine, Yangsan, Republic of Korea.
Jung Won YoonDepartment of Physiology, Pusan National University School of Medicine, Yangsan, Republic of Korea.
Seung-Chul KimDepartment of Obstetrics and Gynecology, Pusan National University School of Medicine, Yangsan, Republic of Korea.
Ho Jin ShinDivision of Hematology-Oncology, Pusan National University School of Medicine, Yangsan, Republic of Korea.
Sang Chul LeeFunctional Genomics Research Center, KRIBB, Daejeon, Republic of Korea.
Jae Ho KimDepartment of Physiology, Pusan National University School of Medicine, Yangsan, Republic of Korea.ORCID 0000-0003-4323-4790
Pusan National University · KRGenome Research Foundation · KRGenomics Medicine (Ireland) · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Circulating angiogenic cells (CACs) have been implicated in the repair of ischemic tissues, and their mobilization from bone marrow is known to be regulated by the activations of chemokine receptors, including CXCR2 and CXCR4. This study was conducted to investigate the role of N-acetylated proline-glycine-proline (Ac-PGP; a collagen-derived chemotactic tripeptide) on CAC mobilization and its therapeutic potential for the treatment of peripheral artery diseases. Ac-PGP was administered daily to a murine hind limb ischemia model, and the effects of Ac-PGP on blood perfusion and CAC mobilization (Sca1

Indexed as

AnimalsCapillariesHindlimbIschemiaMaleMiceMice, Inbred BALB CMice, Inbred C57BLMice, KnockoutMice, TransgenicNeovascularization, PhysiologicPeptidesReceptors, Interleukin-8BPeptidesReceptors, Interleukin-8BAc-PGPCirculating angiogenic cellCXCR2MobilizationNeovascularizationPeripheral artery disease

Identifiers

PMID30474937
PMCPMC6392381
OpenAlexW2902246486

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.