Evidence map›Paper›PMID 30474214›Full record

ArticleBrain and behavior2019

Changes in survival and characteristics among older stroke unit patients-1994 versus 2012.

Angela Susan Labberton, Ole Morten Rønning, Bente Thommessen, Mathias Barra

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Article in Brain and behavior, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

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6citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Angela Susan LabbertonHealth Services Research Unit, Akershus University Hospital, Lørenskog, Norway.ORCID 0000-0002-0047-7103
Ole Morten RønningInstitute of Clinical Medicine, University of Oslo, Lørenskog, Norway.
Bente ThommessenDepartment of Neurology, Akershus University Hospital, Lørenskog, Norway.
Mathias BarraHealth Services Research Unit, Akershus University Hospital, Lørenskog, Norway.ORCID 0000-0002-0022-4042

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTreatment on organized stroke units (SUs) improves survival after stroke, and stroke mortality has decreased worldwide in recent decades; however, little is known of survival trends among SU patients specifically. This study investigates changes in survival and characteristics of older stroke patients receiving SU treatment. MATERIALS &

methodsWe compared 3-year all-cause mortality and baseline characteristics in two cohorts of stroke patients aged ≥60 consecutively admitted to the same comprehensive SU in 1994 (n = 271) and 2012 (n = 546).

resultsThree-year survival was 53.9% in 1994 and 56.0% in 2012, and adjusted hazard ratio (HR) was 0.99 (95% CI: 0.77-1.28). Adjusted 30-day case fatality was slightly higher in 2012, 18.9% versus 16.2%, HR 1.68 (95% CI: 1.14-2.47). There were no significant between-cohort differences in survival beyond 30 days. Patients in 2012 were older (mean age: 78.8 vs. 76.7 years) and more often admitted from nursing homes. There were higher rates of atrial fibrillation (33.7% vs. 21.4%) and malignancy (19.2% vs. 8.9%), and prescription of antiplatelets (46.9% vs. 26.2%) and warfarin (16.3% vs. 5.5%) at admission. Stroke severity was significantly milder in 2012, proportion with mild stroke 66.1% versus 44.3%.

conclusionsThree-year survival in older Norwegian stroke patients treated on an SU remained stable despite improved treatment in the last decades. Differences in background characteristics may explain this lack of difference; patients in 2012 were older, more often living in supported care, and had higher prestroke comorbidity; however, their strokes were milder and risk factors more often treated.

Indexed as

Atrial FibrillationStrokeAgedAged, 80 and overAnticoagulantsCohort StudiesComorbidityFemaleHospital UnitsHumansMaleMiddle AgedNeoplasmsNorwayProportional Hazards ModelsRisk FactorsAnticoagulantsWarfarincerebrovascular disordersmortalityrisk factorsstroke

Identifiers

PMID30474214
PMCPMC6346673

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.