ArticleInternational journal of cancer2019
Increasing risk of uterine cervical cancer among young Japanese women: Comparison of incidence trends in Japan, South Korea and Japanese-Americans between 1985 and 2012.
Article in International journal of cancer, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
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Who cites it
36 citing papers in PubMed.
- Trial
- Tisotumab vedotin in Japanese patients with recurrent/metastatic cervical cancer: Results from the innovaTV 206 study.Cancer science · 2022Trial
- Does Direct-to-Consumer Personal Genetic Testing Improve Gynecological Cancer Screening Uptake among Never-Screened Attendees? A Randomized Controlled Study.International journal of environmental research and public health · 2021Trial
- In-vivo detection of cervical cancer lesions using hyperspectral colposcopy.Scientific reports · 2026Article
- Article
- Emerging trends in cervical cancer incidence among younger Taiwanese generations: an urban-rural comparison.Annals of medicine · 2025Article
- The effects of human papillomavirus vaccination in Japan.Human vaccines & immunotherapeutics · 2025Article
- Probiotics: A New Approach for the Prevention and Treatment of Cervical Cancer.Probiotics and antimicrobial proteins · 2025Review
- Trends and urban-rural disparities in cervical cancer epidemiology in China, 2005-2018.Scientific reports · 2025Article
- Proteogenomic characterization of molecular and cellular targets for treatment-resistant subtypes in locally advanced cervical cancers.Molecular cancer · 2025Article
- Global burden and trends in pre- and post-menopausal gynecological cancer from 1990 to 2019, with projections to 2040: a cross-sectional study.International journal of surgery (London, England) · 2025Article
- Trends in the Disease Burden and Risk Factors of Women's Cancers in China From 1990 to 2019.International journal of public health · 2024Article
- Human papillomavirus vaccine impact on invasive cervical cancer in Japan: Preliminary results from cancer statistics and the MINT study.Cancer science · 2023Article
- Trends in Incidence Rates, Mortality Rates, and Age-Period-Cohort Effects of Cervical Cancer - China, 2003-2017.China CDC weekly · 2022Article
- Trends of cancer mortality in Xi'an City, China: 2005-2020.Journal of cancer research and clinical oncology · 2022Article
- Impact of the cervical cancer awareness months on public interest in Japan: A Google Trends analysis, 2012-2021.Scientific reports · 2022Article
- Trends in cervical cancer incidence and mortality of young and middle adults in Japan.Cancer science · 2022Article
- Effect of Different Educational Interventions on Knowledge of HPV Vaccination and Cervical Cancer among Young Women: A Preliminary Report.International journal of environmental research and public health · 2022Article
- Temporal Changes in Incidence Rates of the Most Common Gynecological Cancers in the Female Population in Central Serbia.Medicina (Kaunas, Lithuania) · 2022Article
- Cervical cancer mortality among young women in Latin America and the Caribbean: trend analysis from 1997 to 2030.BMC public health · 2022Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
In Japan, cervical cancer incidence has increased since the late 1990s especially among young women, despite a decreasing trend in most developed countries. Here, we examined age, period and birth cohort trends in cervical cancer incidence rates from 1985 to 2012. Incidence rates were ascertained using three population-based cancer registries and analyzed using Joinpoint regression and age-period-cohort models. We compared the findings in Japan to trends among Japanese-Americans in the Surveillance, Epidemiology, and End Results Registries and among women in South Korea using the Korea Central Registry. Age-standardized incidence rates in Japan decreased by 1.7% per year (95% confidence interval - 3.3%, 0.0%) until 1997 and thereafter increased by 2.6% per year (1.1%, 4.2%). Incidence rates increased among women under age 50, were stable among women aged 50-54, and decreased or remained stable among women aged 55 and over. The age-standardized incidence rate ratio by birth cohort showed a U-shaped pattern with the lowest rates in women born in the late 1930s and 1940s. In comparison, women born before 1920 and after 1970 had about double the incidence. Increasing risk in recent birth cohorts was not evident in Japanese-American or South Korean women. The trends in Japan may be attributable to increasing prevalence of human papillomavirus (HPV) infection among young women. Screening and vaccination have been shown to be highly effective and would help reverse these trends.
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