Evidence map›Paper›PMID 30474203›Full record

ArticleObesity (Silver Spring, Md.)2019

Association of Maternal Prepregnancy Weight with Offspring Adiposity Throughout Adulthood over 37 Years of Follow-up.

Isabelle Schoppa, Asya Lyass, Nancy Heard-Costa, Sarah D de Ferranti, Caroline Fox, Matthew W Gillman, Ralph D'Agostino, Daniel Levy, Michael M Mendelson

Abstract read
In one paragraph

Article in Obesity (Silver Spring, Md.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Body mass index in parents and their adult offspring: A systematic review and meta-analysis.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2024
    Pooled it
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Isabelle SchoppaFramingham Heart Study, Framingham, Massachusetts, USA.
Asya LyassFramingham Heart Study, Framingham, Massachusetts, USA.
Nancy Heard-CostaFramingham Heart Study, Framingham, Massachusetts, USA.
Sarah D de FerrantiDepartment of Cardiology, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Caroline FoxFramingham Heart Study, Framingham, Massachusetts, USA.
Matthew W GillmanDepartment of Population Medicine, Harvard Pilgrim Health Care Institute, Harvard Medical School, Boston, Massachusetts, USA.
Ralph D'AgostinoFramingham Heart Study, Framingham, Massachusetts, USA.
Daniel LevyFramingham Heart Study, Framingham, Massachusetts, USA.
Michael M MendelsonFramingham Heart Study, Framingham, Massachusetts, USA.ORCID 0000-0001-7590-3958

Funding

Framingham Project/LevyZIAHL006001 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI LEVY, DANIEL · 2009 to 2025
$51.1M
Circulating Epigenetic Biomarkers for Personalized Cardiovascular Disease PreventionK99HL136875 · NHLBI · BOSTON CHILDREN'S HOSPITAL · PI MENDELSON, MICHAEL MAXWELL · 2017 to 2018
$330k
THE FRAMINGHAM HEART STUDY-N01HC25195-268025195-268025195N01HC025195 · HC · TRUSTEES OF BOSTON UNIVERSITY · PI WOLF, PHILIP A · 2002 to 2006
–
NHLBI NIH HHS K99 HL136875NHLBI NIH HHS N01 HC025195NIH HHS N01-HC-25195
6 · The paper itself

Abstract

objectiveThis study aimed to determine the relation of maternal prepregnancy weight with offspring BMI across adulthood from almost 40 years of follow-up.

methodsBMI was measured in Framingham Heart Study Offspring cohort participants between 1971 and 2008. The association of maternal prepregnancy weight category (ascertained via direct measure and questionnaire) with serial offspring BMI, overweight, obesity, and change in BMI over time was tested, adjusted for age, sex, and a BMI genetic risk score; secondary models additionally adjusted for physical activity, dietary factors, smoking, education, and familial relatedness.

resultsAmong 863 participants at initial assessment (83 exposed and 780 controls), mean (SD) age was 33 (10) years, 53% were female, and mean BMI was 24.5 (4.1) kg/m

conclusionsMaternal prepregnancy weight is associated with greater offspring BMI throughout adulthood, with more rapid weight acceleration in early and midadulthood.

Indexed as

AdiposityAdultCohort StudiesFemaleFollow-Up StudiesGestational Weight GainHumansLongitudinal StudiesMaleObesityRisk Factors

Identifiers

PMID30474203
PMCPMC6309198

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.