ArticleGenetic epidemiology2019
Estimating cross-population genetic correlations of causal effect sizes.
Article in Genetic epidemiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
58 citing papers in PubMed, 1 synthesis or guideline pooled it, 98 citations in OpenAlex.
- Causal effects on complex traits are similar for common variants across segments of different continental ancestries within admixed individuals.Nature genetics · 2023Pooled it
- Data Representation Bias and Conditional Distribution Shift Drive Predictive Performance Disparities in Multi-Population Machine Learning.bioRxiv : the preprint server for biology · 2026Article
- The Biobank Rare Variant consortium powers the discovery of rare genetic associations through global collaboration.medRxiv : the preprint server for health sciences · 2026Article
- Ancestral diversity in complex disease genetics: from discovery to translation.Nature reviews. Genetics · 2026Review
- Incorporating external risk information with the Cox model under population heterogeneity: applications to trans-ancestry polygenic hazard scores.Journal of the Royal Statistical Society. Series A, (Statistics in Society) · 2026Article
- Representation in genetic studies affects inference about genetic architecture.bioRxiv : the preprint server for biology · 2026Article
- Mind the gap: Characterizing bias due to population mismatch in two-sample Mendelian randomization.American journal of human genetics · 2026Article
- Optimizing multi-breed joint genomic prediction issues in numerically small breeds for sex-limited trait in a loosely structured dairy cattle breeding system.Tropical animal health and production · 2025Article
- Fine-scale population structure and widespread conservation of genetic effect sizes between human groups across traits.Nature genetics · 2025Article
- Article
- Genes with differential expression across ancestries are enriched in ancestry-specific disease effects likely due to gene-by-environment interactions.American journal of human genetics · 2024Article
- Rare coding variant analysis for human diseases across biobanks and ancestries.Nature genetics · 2024Article
- Causal relevance of different blood pressure traits on risk of cardiovascular diseases: GWAS and Mendelian randomisation in 100,000 Chinese adults.Nature communications · 2024Article
- Cross-ancestry genetic architecture and prediction for cholesterol traits.Human genetics · 2024Article
- Risk factors affecting polygenic score performance across diverse cohorts.medRxiv : the preprint server for health sciences · 2024Article
- Bayesian approach to assessing population differences in genetic risk of disease with application to prostate cancer.PLoS genetics · 2024Article
- Genetic control of DNA methylation is largely shared across European and East Asian populations.Nature communications · 2024Article
- Recent advances in polygenic scores: translation, equitability, methods and FAIR tools.Genome medicine · 2024Review
- Ancestry-specific regulatory and disease architectures are likely due to cell-type-specific gene-by-environment interactions.medRxiv : the preprint server for health sciences · 2023Article
- Assessing efficiency of fine-mapping obesity-associated variants through leveraging ancestry architecture and functional annotation using PAGE and UKBB cohorts.Human genetics · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 3 countries.
Funding
Abstract
Recent studies have examined the genetic correlations of single-nucleotide polymorphism (SNP) effect sizes across pairs of populations to better understand the genetic architectures of complex traits. These studies have estimated
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.