ArticleObstetrics & gynecology science2018
Isotretinoin exposure in pregnant women in Korea.
Article in Obstetrics & gynecology science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
5 citing papers in PubMed, 12 citations in OpenAlex.
- A Pilot Evaluation of the Adequacy of Prenatal Vitamins to Cover Dietary Deficits During Pregnancy and Lactation.Reproductive, female and child health · 2025Article
- Pregnancy and neonatal outcomes after periconceptional exposure to isotretinoin in Koreans.Obstetrics & gynecology science · 2022Article
- The rates of major malformations after gestational exposure to isotretinoin: a systematic review and meta-analysis.Obstetrics & gynecology science · 2021Article
- Non-compliance with pregnancy prevention recommendations for isotretinoin in Korea between 2019-2020.Obstetrics & gynecology science · 2021Article
- Vitamin A and Pregnancy: A Narrative Review.Nutrients · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveIsotretinoin is a notorious teratogen otherwise used for the treatment of acne vulgaris. Some countries, including those in North America and the European Union, implemented the pregnancy prevention program (PPP); however, no PPP has yet been established in South Korea. So the aim of this study was to evaluate the rate of pregnant women exposed to isotretinoin among the callers of the Korean Mother Safe Counseling Center.
methodsThis is a prospective cohort study. We evaluated the demographic characteristics, obstetric history, and isotretinoin exposure of pregnant women based on the mother safe registry from April 2010 to July 2016.
resultsAmong 22,374 callers, 650 (2.9%) pregnant women were exposed to isotretinoin. The mean age was 29.0±4.4 years in the isotretinoin-exposed group and 32.0±4.2 years in the unexposed group (
conclusionApproximately 80% of pregnant women are exposed to isotretinoin within the recommended 30 days of contraception or during pregnancy. Therefore, the PPP has to be established in South Korea.
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Registered trials
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