Evidence map›Paper›PMID 30473742›Full record

SynthesisOxidative medicine and cellular longevity2018

Relevance of Trypanothione Reductase Inhibitors on

Andréa Aparecida Santos Mendonça, Camila Morais Coelho, Marcia Paranho Veloso, Ivo Santana Caldas, Reggiani Vilela Gonçalves, Antônio Lucio Teixeira, Aline Silva de Miranda, Rômulo Dias Novaes

Open access · hybridAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Oxidative medicine and cellular longevity, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Review
  3. Trypanocidal Treatment for Chronic Chagas Disease: Past, Present, and Future.Revista da Sociedade Brasileira de Medicina Tropical · 2025
    Review
  4. Article
  5. Article
  6. ACS omega · 2022
    Article
  7. Current trends in the pharmacological management of Chagas disease.International journal for parasitology. Drugs and drug resistance · 2020
    Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Andréa Aparecida Santos MendonçaInstitute of Biomedical Sciences, Federal University of Alfenas, Alfenas, 37130-001 Minas Gerais, Brazil.
Camila Morais CoelhoFaculty of Pharmaceutical Sciences, Federal University of Alfenas, Alfenas, 37130-001 Minas Gerais, Brazil.
Marcia Paranho VelosoFaculty of Pharmaceutical Sciences, Federal University of Alfenas, Alfenas, 37130-001 Minas Gerais, Brazil.
Ivo Santana CaldasInstitute of Biomedical Sciences, Federal University of Alfenas, Alfenas, 37130-001 Minas Gerais, Brazil.ORCID 0000-0002-4937-2425
Reggiani Vilela GonçalvesDepartment of Animal Biology, Federal University of Viçosa, Viçosa, 36570-000 Minas Gerais, Brazil.ORCID 0000-0002-5831-3590
Antônio Lucio TeixeiraInterdisciplinary Laboratory of Medical Investigation, School of Medicine, Federal University of Minas Gerais, Belo Horizonte, 30130-100 Minas Gerais, Brazil.ORCID 0000-0002-9621-5422
Aline Silva de MirandaInterdisciplinary Laboratory of Medical Investigation, School of Medicine, Federal University of Minas Gerais, Belo Horizonte, 30130-100 Minas Gerais, Brazil.ORCID 0000-0003-2811-7924
Rômulo Dias NovaesInstitute of Biomedical Sciences, Federal University of Alfenas, Alfenas, 37130-001 Minas Gerais, Brazil.ORCID 0000-0002-3186-5328
Universidade Federal de Alfenas · BRUniversidade Federal de Minas Gerais · BRUniversidade Federal de Viçosa · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Due to the rudimentary antioxidant defenses in

Indexed as

AnimalsAntiprotozoal AgentsEnzyme InhibitorsHumansMice, Inbred BALB CNADH, NADPH OxidoreductasesTrypanosoma cruziAntiprotozoal AgentsEnzyme InhibitorsNADH, NADPH Oxidoreductasestrypanothione reductase

Identifiers

PMID30473742
PMCPMC6220389
OpenAlexW2898268921

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.