Evidence map›Paper›PMID 30473713›Full record

ArticleAllergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology2018

Fetal cord blood and tissue immune responses to chronic placental inflammation and chorioamnionitis.

Anne Marie Singh, Michael G Sherenian, Kwang-Youn Kim, Kristin A Erickson, Amy Yang, Karen Mestan, Linda M Ernst, Rajesh Kumar

Open access · goldAbstract read
In one paragraph

Article in Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Immunobiology of Acute Chorioamnionitis.Frontiers in immunology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Anne Marie Singh *1Division of Allergy and Immunology, Department of Pediatrics, Northwestern Feinberg School of Medicine, Ann and Robert H. Lurie Children's Hospital of Chicago, 255 E Chicago Ave, Box #60, Chicago, IL 60611 USA.
Michael G Sherenian *1Division of Allergy and Immunology, Department of Pediatrics, Northwestern Feinberg School of Medicine, Ann and Robert H. Lurie Children's Hospital of Chicago, 255 E Chicago Ave, Box #60, Chicago, IL 60611 USA.
Kwang-Youn Kim2Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL USA.
Kristin A Erickson6Department of Medicine, Northwestern Feinberg School of Medicine, Chicago, IL USA.
Amy Yang3Biostatistics Collaboration Center, Northwestern University Feinberg School of Medicine, Chicago, IL USA.
Karen Mestan4Division of Neonatology, Ann and Robert H. Lurie Children's Hospital of Chicago, Chicago, IL USA.
Linda M Ernst5Department of Pathology and Laboratory Medicine, Northshore University Health System, Evanston, IL USA.
Rajesh Kumar1Division of Allergy and Immunology, Department of Pediatrics, Northwestern Feinberg School of Medicine, Ann and Robert H. Lurie Children's Hospital of Chicago, 255 E Chicago Ave, Box #60, Chicago, IL 60611 USA.
Lurie Children's Hospital · USNorthwestern University · USNorthShore University HealthSystem · US

Funding

S. aureus and Regulatory T cells in the Failure of Oral ToleranceK23AI100995 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI SINGH, ANNE MARIE · 2013 to 2017
$689k
NIAID NIH HHS K23 AI100995
6 · The paper itself

Abstract

backgroundChorioamnionitis is a risk factor for future asthma development. Animal models of chorioamnionitis demonstrate increased T

methodsWe enrolled two cohorts to evaluate T

resultsIn the live birth subjects with chronic placental inflammation we observed an increased proportion of RORγt

conclusionExposure to chorioamnionitis in utero may affect immune activation in neonates with an increased frequency of RORγt

Indexed as

AsthmaChorioamnionitisFoxp3PediatricsRORγtT cells

Identifiers

PMID30473713
PMCPMC6240933
OpenAlexW2897699885

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.