Evidence map›Paper›PMID 30473693›Full record

ArticleFrontiers in immunology2018

IgG Induced by Vaccination With

Ana Clara Gazzinelli-Guimarães, Pedro Henrique Gazzinelli-Guimarães, Denise Silva Nogueira, Fabrício Marcus Silva Oliveira, Fernando Sérgio Barbosa, Chiara Cássia Oliveira Amorim, Mariana Santos Cardoso, Lucas Kraemer, Marcelo Vidigal Caliari, Milena Apetito Akamatsu and 10 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.

  1. Pooled it
  2. The Effects ofMicroorganisms · 2026
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  6. Protective immune response in rainbow trout (Frontiers in immunology · 2025
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  12. Review
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  16. The yin and yang of human soil-transmitted helminth infections.International journal for parasitology · 2021
    Review
  17. Article
  18. Circulating Nestin-GFPStem cell reviews and reports · 2021
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 4 institutions in 2 countries.

Ana Clara Gazzinelli-GuimarãesInstituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Pedro Henrique Gazzinelli-GuimarãesInstituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Denise Silva NogueiraInstituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Fabrício Marcus Silva OliveiraInstituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Fernando Sérgio BarbosaInstituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Chiara Cássia Oliveira AmorimInstituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Mariana Santos CardosoInstituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Lucas KraemerInstituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Marcelo Vidigal CaliariInstituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Milena Apetito AkamatsuBioIndustrial Division, Butantan Institute, Sao Paulo Secretary of Health, São Paulo, Brazil.
Paulo Lee HoBioIndustrial Division, Butantan Institute, Sao Paulo Secretary of Health, São Paulo, Brazil.
Kathryn Marie JonesTexas Children's Hospital Center for Vaccine Development, Department of Pediatric Tropical Medicine, National School of Tropical Medicine, Baylor College of Medicine, Houston, TX, United States.
Jill WeatherheadTexas Children's Hospital Center for Vaccine Development, Department of Pediatric Tropical Medicine, National School of Tropical Medicine, Baylor College of Medicine, Houston, TX, United States.
Maria Elena BottazziTexas Children's Hospital Center for Vaccine Development, Department of Pediatric Tropical Medicine, National School of Tropical Medicine, Baylor College of Medicine, Houston, TX, United States.
Peter J HotezTexas Children's Hospital Center for Vaccine Development, Department of Pediatric Tropical Medicine, National School of Tropical Medicine, Baylor College of Medicine, Houston, TX, United States.
Bin ZhanTexas Children's Hospital Center for Vaccine Development, Department of Pediatric Tropical Medicine, National School of Tropical Medicine, Baylor College of Medicine, Houston, TX, United States.
Daniella Castanheira BartholomeuInstituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Remo Castro RussoInstituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Lilian Lacerda BuenoInstituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Ricardo Toshio FujiwaraInstituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Universidade Federal de Minas Gerais · BRTexas Children's Hospital · USBaylor College of Medicine · USInstituto Butantan · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human ascariasis has a global and cosmopolitan distribution, and has been characterized as the most prevalent neglected tropical disease worldwide. The development of a preventive vaccine is highly desirable to complement current measures required for this parasitic infection control and to reduce chronic childhood morbidities. In the present study, we describe the mechanism of protection elicited by a preventive vaccine against ascariasis. Vaccine efficacy was evaluated after immunization with three different

Indexed as

Adjuvants, ImmunologicAnimalsAntibodies, HelminthAntigens, HelminthAscariasisAscaris suumFemaleImmunityImmunizationImmunoglobulin GInterleukin-10LarvaLungMaleMiceMice, Inbred BALB CAdjuvants, ImmunologicAntibodies, HelminthAntigens, HelminthImmunoglobulin GInterleukin-10Protective AgentsVaccinesantigensAscarishumoral responseimmune responsevaccine

Identifiers

PMID30473693
PMCPMC6238660
OpenAlexW2899648713

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.