ArticleMedical science monitor : international medical journal of experimental and clinical research2018
Effect of Age on Prognosis of Gastric Signet-Ring Cell Carcinoma: A SEER Database Analysis.
Article in Medical science monitor : international medical journal of experimental and clinical research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Development and validation of nomograms for predicting overall survival and cancer-specific survival in female gastric signet-ring cell carcinoma: a SEER database analysis.Translational cancer research · 2026Article
- Individualized prediction tool for patients with metastatic gastric signet cell carcinoma.Scientific reports · 2025Article
- A prognostic nomogram utilized lymph node ratio for signet ring cell gastric cancer patients post-surgery.Journal of gastrointestinal oncology · 2025Article
- Survival analysis of gastric malignancy patients: identifying key prognostic factors.Translational cancer research · 2025Article
- A novel web-based dynamic prognostic nomogram for gastric signet ring cell carcinoma: a multicenter population-based study.Frontiers in immunology · 2024Article
- Development and validation of a novel nomogram for postoperative overall survival of patients with primary gastric signet-ring cell carcinoma: a population study based on SEER database.Journal of cancer research and clinical oncology · 2023Article
- Prognostic Survival Significance of Signet Ring Cell (SRC) Gastric Cancer: Retrospective Analysis from a Single Western Center.Journal of personalized medicine · 2023Article
- Artificial intelligence annotated clinical-pathologic risk model to predict outcomes of advanced gastric cancer.Frontiers in oncology · 2023Article
- A population-based predictive model to identify patients with signet ring cell carcinoma of the stomach who are most suitable for primary tumor resection.World journal of surgical oncology · 2022Article
- Is there still a place for conventional histopathology in the age of molecular medicine? Laurén classification, inflammatory infiltration and other current topics in gastric cancer diagnosis and prognosis.Histology and histopathology · 2021Review
- Prognostic Nomogram for Predicting Overall Survival of Solitary Bone Plasmacytoma Patients: A Large Population-Based Study.International journal of general medicine · 2021Article
- Development and validation of prognostic nomogram based on log odds of positive lymph nodes for patients with gastric signet ring cell carcinoma.Chinese journal of cancer research = Chung-kuo yen cheng yen chiu · 2020Article
- The Clinicopathological Characteristics And Genetic Alterations of Signet-ring Cell Carcinoma in Gastric Cancer.Cancers · 2020Article
- Identification of key genes and pathways in gastric signet ring cell carcinoma based on transcriptome analysis.World journal of clinical cases · 2020Article
- Postoperative Radiotherapy Improves Survival in Gastric Signet-Ring Cell Carcinoma: a SEER Database Analysis.Journal of gastric cancer · 2019Article
- Identification of Key Genes and Circular RNAs in Human Gastric Cancer.Medical science monitor : international medical journal of experimental and clinical research · 2019Article
- Survival Analysis of Cancer Patients in North Eastern Nigeria from 2004 - 2017 - A Kaplan - Meier Method.Open access Macedonian journal of medical sciences · 2019Article
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6 authors.
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Abstract
BACKGROUND Age is a prognostic factor for multiple malignancies. In this study, we aimed to assess the effect of age on the cancer-specific survival (CSS) of patients with gastric signet-ring cell carcinoma (SRC). MATERIAL AND METHODS Information on patients with gastric SRC was extracted from the Surveillance, Epidemiology, and End Results database. Chi-squared tests were used to demonstrate distribution differences, and Kaplan-Meier analysis and Cox regression models were used to analyze the impact of age on CSS. RESULTS A total of 4596 patients were enrolled and divided into 3 subgroups according to age (<45, 45-74, and >74 years old). Higher percentages of T4, N2, and M1 disease were observed in the <45-year-old group (all P<0.001). Kaplan-Meier plots showed that the youngest group had the most favorable 5-year CSS rate (36.3%), which remained true after stratification according to tumor stage. Multivariate Cox regression models demonstrated a poorer survival outcome for >74-year-old than for <45-year-old patients (hazard ratio 1.841, 95% confidence interval 1.636-2.071; P<0.001). CONCLUSIONS Young age is associated with improved survival, even though younger patients generally present with a more advanced-stage disease.
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