Evidence map›Paper›PMID 30473456›Full record

ArticleArthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association2019

Abnormal Biomechanics at 6 Months Are Associated With Cartilage Degeneration at 3 Years After Anterior Cruciate Ligament Reconstruction.

Tomohiro Shimizu, Michael A Samaan, Matthew S Tanaka, Valentina Pedoia, Richard B Souza, Xiaojuan Li, C Benjamin Ma

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 3 pooled it
7.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 3 syntheses or guidelines pooled it, 69 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Gait Mechanics in Women of the ACL-SPORTS Randomized Control Trial: Interlimb Symmetry Improves Over Time Regardless of Treatment Group.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2019
    Trial
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Tomohiro ShimizuDepartment of Orthopaedic Surgery, University of California, San Francisco, San Francisco, California, U.S.A.; Department of Orthopaedic Surgery, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan.
Michael A SamaanMusculoskeletal Quantitative Imaging Research Group, Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, California, U.S.A.
Matthew S TanakaMusculoskeletal Quantitative Imaging Research Group, Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, California, U.S.A.
Valentina PedoiaMusculoskeletal Quantitative Imaging Research Group, Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, California, U.S.A.
Richard B SouzaMusculoskeletal Quantitative Imaging Research Group, Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, California, U.S.A.; Department of Physical Therapy and Rehabilitation Science, University of California, San Francisco, San Francisco, California, U.S.A.
Xiaojuan LiMusculoskeletal Quantitative Imaging Research Group, Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, California, U.S.A.
C Benjamin MaDepartment of Orthopaedic Surgery, University of California, San Francisco, San Francisco, California, U.S.A.. Electronic address: maben@orthosurg.ucsf.edu.
Quantitative BioSciences · USUniversity of California, San Francisco · US

Funding

Translation of Quantitative Imaging in OsteoarthritisP50AR060752 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SOUZA, RICHARD BRIAN · 2011 to 2015
$6.2M
Mentoring Biomechanics Research in OsteoarthritisK24AR072133 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Richard Brian Souza · 2018 to 2026
$1.5M
Longitudinal Assessment of the Effects of Hip Arthroscopy on Articular Cartilage Biochemistry through a Novel Quantitative MRI-Based ApproachF32AR069458 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SAMAAN, MICHAEL A · 2016 to 2017
$124k
NIAMS NIH HHS F32 AR069458NIAMS NIH HHS K24 AR072133NIAMS NIH HHS P50 AR060752
6 · The paper itself

Abstract

purposeTo investigate the changes in landing biomechanics over a 3-year period and their correlation with cartilage degenerative changes in the medial tibiofemoral joint of the knee after anterior cruciate ligament reconstruction (ACLR) using magnetic resonance T1ρ mapping.

methodsThirty-one anterior cruciate ligament-injured patients underwent magnetic resonance imaging of the injured knee before ACLR and 3 years after ACLR, as well as biomechanical analysis of a drop-landing task at 6 months and 3 years after ACLR. Sixteen healthy individuals were recruited and underwent knee magnetic resonance imaging and biomechanical assessment during a drop-landing task. T1ρ cartilage relaxation times were calculated for the medial femur and tibia.

resultsACLR patients exhibited increased peak vertical ground reaction force (VGRF), VGRF impulse, peak knee flexion moment (KFM), and KFM impulse from 6 months to 3 years (P < .001 for each). Although the ACLR knees showed significantly lower peak VGRF and KFM at 6 months (P < .001 for both) when compared with the controls, there were no significant differences at 3 years. At 3 years, ACLR patients showed higher T1ρ values over the medial femur (P < .001) and tibia (P = .012) when compared with their preoperative values and with healthy control values. Within the ACLR group, side-to-side differences in peak VGRF and sagittal knee biomechanics at 6 months were associated with increased T1ρ values from baseline to 3 years.

conclusionsThe results of this longitudinal study show that landing biomechanics are altered after ACLR but biomechanical abnormalities tend to recover at 3 years after ACLR. Differences in lower-extremity mechanics during a landing task at 6 months may be associated with cartilage degeneration at 3 years after anterior cruciate ligament injury and reconstruction. LEVEL OF EVIDENCE: Level II, prospective trial.

Indexed as

AdultAnterior Cruciate LigamentAnterior Cruciate Ligament InjuriesAnterior Cruciate Ligament ReconstructionBiomechanical PhenomenaCase-Control StudiesFemaleHumansKnee JointLongitudinal StudiesLower ExtremityMagnetic Resonance ImagingMalePostoperative ComplicationsProspective StudiesRange of Motion, Articular

Identifiers

PMID30473456
PMCPMC6361700
OpenAlexW2900694788

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.