Evidence map›Paper›PMID 30473192›Full record

ReviewInternational review of neurobiology2018

Neuroimaging Applications in Dystonia.

Kristina Simonyan

Registry-linked trialOpen access · greenAbstract readReview
In one paragraph

Review in International review of neurobiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03042962 (Brain Networks in Dystonia), which is not on this map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
16.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03042962 recruitingnot on this map

Brain Networks in Dystonia

TypeobservationalSponsorMassachusetts Eye and Ear InfirmaryRan2015 to 2027Enrolled141ConditionsSpasmodic Dysphonia, Singer's Dystonia, Writer's Cramp, Musician's Focal Hand DystoniaArmsMRI, Blood draw
3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Brain-Computer Interface Improves Symptoms of Isolated Focal Laryngeal Dystonia: A Single-Blind Study.Movement disorders : official journal of the Movement Disorder Society · 2026
    Article
  4. Generalized dystonia unraveled: Molecular mechanisms, diagnostic strategies, and treatment paradigms.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
    Review
  5. Abnormal Brain Iron Metabolism is Linked to Altered Neural Function in Isolated Laryngeal Dystonia.Movement disorders : official journal of the Movement Disorder Society · 2025
    Article
  6. Article
  7. Review
  8. Understanding Anxiety in Cervical Dystonia: An Imaging Study.Movement disorders clinical practice · 2024
    Article
  9. Temporal Signature of Task-Specificity in Isolated Focal Laryngeal Dystonia.Movement disorders : official journal of the Movement Disorder Society · 2023
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Kristina SimonyanDepartment of Otolaryngology, Massachusetts Eye and Ear Infirmary, Boston, MA, United States; Department of Neurology, Massachusetts General Hospital, Boston, MA, United States; Harvard Medical School, Boston, MA, United States. Electronic address: kristina_simonyan@meei.harvard.edu.
Massachusetts General Hospital · US

Funding

Imaging genetics of spasmodic dysphoniaR01DC011805 · NIDCD · MASSACHUSETTS EYE AND EAR INFIRMARY · PI Kristina Simonyan · 2012 to 2026
$8.8M
Voice tremor in spasmodic dysphonia: central mechanisms and treatment responseR01DC012545 · NIDCD · MASSACHUSETTS EYE AND EAR INFIRMARY · PI SIMONYAN, KRISTINA · 2012 to 2021
$5.2M
Brain Networks in DystoniaR01NS088160 · NINDS · MASSACHUSETTS EYE AND EAR INFIRMARY · PI SIMONYAN, KRISTINA · 2015 to 2019
$2.4M
NIDCD NIH HHS R01 DC011805NIDCD NIH HHS R01 DC012545NINDS NIH HHS R01 NS088160
6 · The paper itself

Abstract

Dystonia is a neurological disorder characterized by involuntary, repetitive movements. Although the precise mechanisms of dystonia development remain unknown, the diversity of its clinical phenotypes is thought to be associated with multifactorial pathophysiology, which is linked not only to alterations of brain organization, but also environmental stressors and gene mutations. This chapter will present an overview of the pathophysiology of isolated dystonia through the lens of applications of major neuroimaging methodologies, with links to genetics and environmental factors that play a prominent role in symptom manifestation.

Indexed as

BrainDystonic DisordersGray MatterWhite MatterHumansMagnetic Resonance ImagingNeuroimagingPositron-Emission TomographyDiffusion imagingFunctional magnetic resonance imagingIsolated dystoniaNeuroreceptor mappingPathophysiologyPositron emission tomographyVoxel-based morphometry

Identifiers

PMID30473192
PMCPMC6331056
OpenAlexW2896718777

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.