Evidence map›Paper›PMID 30473016›Full record

ArticleBiophysical journal2018

Piconewton Mechanical Forces Promote Neurite Growth.

Vittoria Raffa, Francesca Falcone, Sara De Vincentiis, Alessandro Falconieri, Maria P Calatayud, Gerardo F Goya, Alfred Cuschieri

Open access · hybridAbstract read
In one paragraph

Article in Biophysical journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 43 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Mechanical Forces Guide Axon Growth through the Nigrostriatal Pathway in an Organotypic Model.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. The role of mechanics in axonal stability and development.Seminars in cell & developmental biology · 2023
    Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Manipulation of Axonal Outgrowth via Exogenous Low Forces.International journal of molecular sciences · 2020
    Review
  19. Article
  20. Extremely Low Forces Induce Extreme Axon Growth.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Vittoria RaffaThe Institute for Medical Science and Technology, University of Dundee, Dundee, United Kingdom; Department of Biology, Università di Pisa, Pisa, Italy. Electronic address: vittoria.raffa@unipi.it.
Francesca FalconeThe Institute for Medical Science and Technology, University of Dundee, Dundee, United Kingdom; Department of Biology, Università di Pisa, Pisa, Italy.
Sara De VincentiisDepartment of Biology, Università di Pisa, Pisa, Italy.
Alessandro FalconieriDepartment of Biology, Università di Pisa, Pisa, Italy.
Maria P CalatayudInstituto de Nanociencia de Aragón, Universidad de Zaragoza, Mariano Esquillor, Zaragoza, Spain.
Gerardo F GoyaInstituto de Nanociencia de Aragón, Universidad de Zaragoza, Mariano Esquillor, Zaragoza, Spain.
Alfred CuschieriThe Institute for Medical Science and Technology, University of Dundee, Dundee, United Kingdom.
University of Pisa · ITUniversidad de Zaragoza · ESUniversity of Dundee · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Investigations over half a century have indicated that mechanical forces induce neurite growth, with neurites elongating at a rate of 0.1-0.3 μm h

Indexed as

Mechanical PhenomenaAnimalsBiomechanical PhenomenaFerric CompoundsNanoparticlesNeuritesPC12 CellsRatsFerric Compoundsferric oxide

Identifiers

PMID30473016
PMCPMC6303536
OpenAlexW2896392907

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.