Evidence map›Paper›PMID 30472968›Full record

ArticlePublic health nutrition2019

Changes in socio-economic status and lipoproteins in Chilean adolescents: a 16-year longitudinal study.

Zachary J Madewell, Estela Blanco, Raquel Burrows, Betsy Lozoff, Sheila Gahagan

Open access · bronzeAbstract read
In one paragraph

Article in Public health nutrition, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Low socioeconomic status, insulin resistance, asthma, and depression: A syndemic framework in Brazilian adolescents.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2026
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Zachary J MadewellUniversity of California, San Diego/San Diego State University, PhD Program in Public Health (Epidemiology), 9500 Gilman Drive, La Jolla, CA 92093, CA, USA.
Estela BlancoUniversity of California, San Diego, Department of Pediatrics, La Jolla, CA, USA.
Raquel BurrowsUniversidad de Chile, Instituto de Nutrición y Tecnología de los Alimentos, Santiago, Chile.
Betsy LozoffUniversity of Michigan, Center for Human Growth & Development, Ann Arbor, MI, USA.
Sheila GahaganUniversity of California, San Diego, Department of Pediatrics, La Jolla, CA, USA.
University of Michigan–Ann Arbor · USSan Diego State University · USUniversity of California, San Diego · USUniversity of Chile · CL

Funding

NEUROMATURATION DELAYS IN IRON DEFICIENT ANEMIC INFANTSR01HD033487 · NICHD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI GAHAGAN, SHEILA, LOZOFF, BETSY · 1997 to 2016
$8.8M
Biopsychosocial Determinants of Adolescent Obesity/Cardiovascular RiskR01HL088530 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI GAHAGAN, SHEILA · 2008 to 2017
$5.0M
NHLBI NIH HHS R01 HL088530NICHD NIH HHS R01 HD033487
6 · The paper itself

Abstract

objectiveThe present longitudinal study assessed whether changes in socio-economic status (SES) from infancy to adolescence were associated with plasma lipoprotein concentrations in adolescence, of which low HDL-cholesterol (HDL-C) and high LDL-cholesterol (LDL-C), TAG and total cholesterol (TC) concentrations are associated with higher cardiovascular risk.

designSES, assessed using the modified Graffar Index, was calculated at 1, 5, 10 and 16 years. Principal components factor analysis with varimax rotation extracted two orthogonal SES factors, termed 'environmental capital' and 'social capital'. Generalized linear models were used to analyse associations between environmental and social capital at 1 and 16 years and outcomes (HDL-C, LDL-C, TAG, TC) at 16 years, as well as changes in environmental and social capital from 1-5, 5-10, 10-16 and 1-16 years, and outcomes at 16 years.

settingSantiago, Chile.ParticipantsWe evaluated 665 participants from the Santiago Longitudinal Study enrolled at infancy in Fe-deficiency anaemia studies and examined every 5 years to age 16 years.

resultsSocial capital in infancy was associated with higher HDL-C in adolescence. Environmental capital in adolescence was associated with higher LDL-C and TC during adolescence. Changing environmental capital from 1-16 years was associated with higher LDL-C. Changing environmental capital from 1-5 and 1-16 years was associated with higher TC.

conclusionsImprovements in environmental capital throughout childhood were associated with less healthy LDL-C and TC concentrations in adolescence. We found no evidence of associations between changing environmental capital and HDL-C or TAG, or changing social capital and HDL-C, LDL-C, TAG or TC.

Indexed as

Social CapitalSocial ClassAdolescentCardiovascular DiseasesChildChild Nutritional Physiological PhenomenaChild, PreschoolChileCholesterolCholesterol, HDLCholesterol, LDLEnvironmentFemaleHumansInfantLinear ModelsCholesterolCholesterol, HDLCholesterol, LDLLipoproteinsTriglyceridesChild healthChileLipoproteinsSocio-economic status

Identifiers

PMID30472968
PMCPMC6351179
OpenAlexW2902122139

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.