ArticleJournal of pathology and translational medicine2019
Primary Malignant Melanoma of the Breast: A Report of Two Cases.
Article in Journal of pathology and translational medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 16 citations in OpenAlex.
- First Case of Primary Breast Melanoma in Central America: Case Report and Literature Review.Clinical case reports · 2025Article
- Primary nipple melanoma in a patient with breast cancer: A diagnosis to consider.Radiology case reports · 2024Article
- Comprehensive Literature Review on Melanoma of Unknown Primary Site Triggered by an Intriguing Case Report.Diagnostics (Basel, Switzerland) · 2024Article
- Review
- [Metastatic breast melanoma in a man: Case report].Revista medica del Instituto Mexicano del Seguro Social · 2024Article
- Primary Malignant Melanoma of the Breast Presenting as a Breast Abscess: A Case Report.Journal of the Korean Society of Radiology · 2023Article
- Primary Melanoma of the Breast Parenchyma: An Oncoplastic Approach.Plastic and reconstructive surgery. Global open · 2020Article
- Uncommon Subtypes of Malignant Melanomas: A Review Based on Clinical and Molecular Perspectives.Cancers · 2020Review
- Significance of 5-International journal of molecular sciences · 2020Review
- Surgery on primary melanoma of the breast.Translational cancer research · 2019Review
- Nipple Melanoma: A Case Report and Review of the Literature.Case reports in dermatologyArticle
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
Primary malignant melanoma of the breast (PMMB) is a rare tumor with only a few case reports available in the literature. We report two cases of PMMB, one derived from the breast parenchyma and the other from the breast skin. The first case consisted of atypical epithelioid cells without overt melanocytic differentiation like melanin pigments. The tumor cells showed diffuse positivity for S100 protein, tyrosinase, and BRAF V600E. However, the tumor cells were negative for cytokeratin, epithelial membrane antigen, and HMB-45. The second case showed atypical melanocytic proliferation with heavy melanin pigmentation. The tumor cells were positive for S100 protein, HMB-45, tyrosinase, and BRAF V600E. These two cases represent two distinct presentations of PMMB in terms of skin involvement, melanin pigmentation, and HMB-45 positivity. Although PMMB is very rare, the possibility of this entity should be considered in malignant epithelioid neoplasms in the breast parenchyma.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.