ArticleClinical transplantation2019
Risk of adverse maternal and fetal outcomes during pregnancy in living kidney donors: A matched cohort study.
Article in Clinical transplantation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.
- Pregnancy after living kidney donation, a systematic review of the available evidence, and a review of the current guidance.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2022Pooled it
- Donor medicine: An emerging field in nephrology.World journal of nephrology · 2026Review
- Living Donation and Pregnancy-Related Complications: State of the Evidence and Call To Action for Improved Risk Assessment.Clinical journal of the American Society of Nephrology : CJASN · 2024Review
- Pre-gestational counselling for women living with CKD: starting from the bright side.Clinical kidney journal · 2024Review
- Pregnancy Outcomes in Living Kidney Donors: Protocol of a Population-Based Cohort Study in Three Canadian Provinces.Canadian journal of kidney health and disease · 2024Article
- Pregnancy in Living Kidney Donors: An Evidence-Based Review.Current transplantation reports · 2023Article
- Article
- Pregnancy outcomes after living kidney donation from a nationwide population-based cohort study from Korea.Scientific reports · 2022Article
- Long-term Medical Outcomes of Living Kidney Donors.Mayo Clinic proceedings · 2022Review
- Article
- Gender and race/ethnicity differences in living kidney donor demographics: Preference or disparity?Transplantation reviews (Orlando, Fla.) · 2021Review
- Combined detection of ACL and β2-GP1 in diagnosis of adverse pregnancy.American journal of translational research · 2021Article
- Acute IgA-Dominant Glomerulonephritis Associated with Syphilis Infection in a Pregnant Teenager: A New Disease Association.Journal of clinical medicine · 2019Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundWe examined the risk of adverse pregnancy outcomes in primiparous kidney donors compared to matched controls.
methodsFifty-nine women with a history of kidney donation prior to their first pregnancy with normal renal function and no history of kidney disease, diabetes or chronic hypertension were matched 1:4 by age (within 2 years) and race to women with two kidneys using data from an integrated healthcare delivery system. Adverse pregnancy outcomes were defined as preterm delivery (delivery <37 weeks), delivery via cesarean section, gestational hypertension, preeclampsia/eclampsia, gestational diabetes, length of stay in the hospital >3 days, infant death/transfer to acute facility and low birthweight (<2500 g).
resultsLiving kidney donors did not have a higher risk of adverse outcomes compared to matched controls. There was a trend toward an increased risk of preeclampsia/eclampsia in kidney donors but it did not reach statistical significance (Odds ratio [OR]: 2.96, 95% CI: 0.98-8.94, P = 0.06). However, in kidney donors ≤30 years of age, there was a fourfold increased risk of preeclampsia/eclampsia (OR: 4.09, 95% CI: 1.07-15.59, P = 0.04).
conclusionOverall, the risk of pregnancy-associated complications following kidney donation is small but potential female kidney donors should be counseled on the possible increased risk of preeclampsia.
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