ReviewNeoplasia (New York, N.Y.)2019
Hyperpolarized
Abstract readReview
In one paragraph
Review in Neoplasia (New York, N.Y.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 270 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
270citing papers in PubMed, 1 pooled it
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
270 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Metabolic Imaging as Future Technology and Innovation in Brain-Tumour Surgery: A Systematic Review.Current oncology (Toronto, Ont.) · 2025Pooled it
- Multi-Vendor and Multi-Site Characterization ofMagnetic resonance in medicine · 2026Article
- Stable isotopes from Earth science to bedside medicine: beyond tracers and toward mechanistic biomarkers in medical oncology.Medical oncology (Northwood, London, England) · 2026Review
- Hyperpolarized MRI in Oncology-A Review of Clinical Studies and Evaluation of Preclinical Liver Studies.NMR in biomedicine · 2026Review
- Magnetic resonance imaging.Science advances · 2026Review
- Proof-of-Concept Study of Hyperpolarized [1-Radiology. Imaging cancer · 2026Article
- Imaging the hallmarks of cancer.Nature reviews. Cancer · 2026Review
- Clinical Applications of Hyperpolarized Magnetic Resonance Imaging in Brain Tumors: Current Evidence and Future Opportunities.Cancers · 2026Review
- HyperpolarizedResearch square · 2026Article
- ESR Innovation in Focus: Emerging MR methods to image tissue metabolism.European radiology · 2026Article
- Open-Source Multinuclear Low-Field Preclinical MRI Scanner.NMR in biomedicine · 2026Article
- Increasing Infusion Times of Hyperpolarized [1-Magnetic resonance in medicine · 2026Article
- Ultra-low fieldCommunications chemistry · 2026Article
- Pharmacokinetic modeling strategies for dynamic hyperpolarized urea imaging.Magnetic resonance in medicine · 2026Article
- Review
- Probing intratumoral metabolic compartmentalisation in a patient with fumarate hydratase-deficient renal cancer using clinical hyperpolarisedCommunications medicine · 2026Article
- Quantum Life Science: A Paradigm for Life Science Research.ACS nano · 2026Review
- Potential Clinical Applications of HyperpolarizedRecent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer · 2026Review
- HyperpolarizedImaging neuroscience (Cambridge, Mass.) · 2026Article
- Multifunctional Magnetic Resonance Imaging Probes.Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer · 2026Review
210 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
23 authors.
John KurhanewiczDepartment of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA, USA. Electronic address: John.Kurhanewicz@ucsf.edu.
Daniel B VigneronDepartment of Radiology and Biomedical Imaging, University of California at San Francisco, San Francisco, CA, USA.
Jan Henrik Ardenkjaer-LarsenDepartment of Electrical Engineering, Technical University of Denmark, Denmark.
James A BanksonDepartment of Imaging Physics, MD Anderson Medical Center, Houston, TX, USA.
Kevin BrindleDepartment of Biochemistry, University of Cambridge, Cambridge, UK.
Charles H CunninghamSunnybrook Health Sciences Centre, University of Toronto, Toronto, Canada.
Ferdia A GallagherDepartment of Radiology, University of Cambridge, Cambridge, UK.
Kayvan R KeshariDepartment of Radiology, Memorial Sloan Kettering Cancer Center, NY, New York, USA.
Andreas KjaerDepartment of Clinical Physiology, Nuclear Medicine & PET and Cluster for Molecular Imaging, Rigshospitalet and University of Copenhagen, Denmark.
Christoffer LaustsenDepartment of Clinic Medicine, Aarhus University Hospital, Aarhus, Denmark.
David A MankoffDepartment of Radiology, University of Pennsylvania, PA, USA.
Matthew E MerrittDepartment of Biochemistry and Molecular Biology, University of Florida, Gainesville, FL, USA.
Sarah J NelsonDepartment of Radiology and Biomedical Imaging, University of California at San Francisco, San Francisco, CA, USA.
John M PaulyDepartment of Electric Engineering, Stanford University, USA.
Philips LeeFunctional Metabolism Group, Singapore Biomedical Consortium, Agency for Science, Technology and Research, Singapore.
Sabrina RonenDepartment of Radiology and Biomedical Imaging, University of California at San Francisco, San Francisco, CA, USA.
Damian J TylerDepartment of Biomedical Science, University of Oxford, Oxford, UK.
Sunder S RajanCenter for Devices and Radiological Health (CDRH), FDA, White Oak, MD, USA.
Daniel M SpielmanDepartments of Radiology and Electric Engineering, Stanford University, USA.
Lawrence WaldDepartment of Radiology, Harvard Medical School, Boston, MA, USA.
Xiaoliang ZhangDepartment of Radiology and Biomedical Imaging, University of California at San Francisco, San Francisco, CA, USA.
Craig R MalloyAdvanced Imaging Research Center, UT Southwestern Medical Center, Dallas, TX, USA.
Rahim RiziDepartment of Radiology, University of Pennsylvania, PA, USA.
Funding
X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4MUNIVERSITY OF PENNSYLVANIA CAN CTR SUPPORT GRANTP30CA016520 · NCI · UNIVERSITY OF PENNSYLVANIA · PI Robert H. Vonderheide · 1985 to 2026
$222.3MTraining and DisseminationP41EB015891 · NIBIB · STANFORD UNIVERSITY · PI GLOVER, GARY H · 2012 to 2019
$10.7MEnhanced MR for morphological characterization of ligaments, tendons and boneU01EB023829 · NIBIB · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI LI, XIAOJUAN, ZHANG, XIAOLIANG · 2018 to 2024
$1.9MImaging Hepatic Gluconeogenesis with Hyperpolarized DihydroxyacetoneR01DK105346 · NIDDK · UNIVERSITY OF FLORIDA · PI MERRITT, MATTHEW E · 2016 to 2020
$1.7MReproducibility of Hyperpolarized Pyruvate Metabolic Imaging in Prostate CancerR01CA195476 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI HRICAK, HEDVIG, KESHARI, KAYVAN R · 2016 to 2018
$822kGE Diamond DNP PolarizerS10OD016422 · OD · SLOAN-KETTERING INST CAN RESEARCH · PI HRICAK, HEDVIG, KESHARI, KAYVAN R · 2014 to 2014
$600kBritish Heart Foundation FS/10/002/28078British Heart Foundation FS/14/17/30634British Heart Foundation FS/19/18/34252British Heart Foundation RG/11/9/28921Cancer Research UK 16465Cancer Research UK 16628Cancer Research UK 17242Cancer Research UK 28289Medical Research Council G0601490NCI NIH HHS P30 CA008748NCI NIH HHS P30 CA016520NCI NIH HHS R01 CA195476NIBIB NIH HHS P41 EB015891NIBIB NIH HHS U01 EB023829NIDDK NIH HHS R01 DK105346NIH HHS S10 OD016422
Abstract
This white paper discusses prospects for advancing hyperpolarization technology to better understand cancer metabolism, identify current obstacles to HP (hyperpolarized)
Indexed as
Carbon IsotopesAnimalsDisease Models, AnimalHumansMagnetic Resonance ImagingNeoplasmsReproducibility of ResultsTranslational Research, BiomedicalCarbon-13Carbon Isotopes
Identifiers
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LicenceCC BY-NC-ND
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.