Evidence map›Paper›PMID 30472467›Full record

ArticleThe International journal on drug policy2019

Patients' and clinicians' perspectives of co-use of cannabis and opioids for chronic non-cancer pain management in primary care.

Alexis C Cooke, Kelly R Knight, Christine Miaskowski

Abstract read
In one paragraph

Article in The International journal on drug policy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 2 pooled it
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 2 syntheses or guidelines pooled it, 54 citations in OpenAlex.

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  5. Chronic pain among primary fentanyl users: The concept of self-medication.European journal of pain (London, England) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Alexis C CookeDepartment of Psychiatry, University of California, San Francisco CA, United States. Electronic address: alexis.cooke@ucsf.edu.
Kelly R KnightDepartment of Anthropology, History and Social Medicine, University of California, San Francisco CA, United States.
Christine MiaskowskiDepartment of Physiological Nursing, University of California, San Francisco CA, United States.
University of California, San Francisco · US

Funding

Substance Use Disorders Treatment/Services Research Training ProgramT32DA007250 · NIDA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Derek D Satre, Janice Y Tsoh · 1991 to 2026
$7.4M
Examining the Consequences of Reductions in Opioid Prescribing on Patients, Clinical Care, and Community HealthR01DA043631 · NIDA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KNIGHT, KELLY RAY · 2017 to 2021
$2.7M
Pain Management in the Clinic & CommunityR01DA034625 · NIDA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KNIGHT, KELLY RAY · 2013 to 2015
$893k
NIDA NIH HHS R01 DA034625NIDA NIH HHS R01 DA043631NIDA NIH HHS T32 DA007250
6 · The paper itself

Abstract

backgroundThe prevalence of opioid-associated morbidity and mortality underscores the need for research on non-opioid treatments for chronic non-cancer pain (CNCP). Pain is the most common medical condition for which patients request medical cannabis. Limited research indicates that patients are interested in cannabis as a potential addition to or replacement for opioid medication. This analysis reports on CNCP patient and clinician perceptions about the co-use of cannabis and opioids for CNCP management.

methodsWe interviewed 23 clinicians and 46 CNCP patients, using semi-structured interview guides, from six safety-net clinics across the San Francisco Bay Area, and 5 key stakeholders involved in CNCP management. We used a modified grounded theory approach to code and analyze transcripts.

resultsCNCP patients described potential benefits of co-use of cannabis and opioids for pain management and concerns about dosing and addictive potential. Patients reported seeking cannabis when unable to obtain prescription opioids. Clinicians stated that their patients reported cannabis being helpful in managing pain symptoms. Clinicians expressed concerns about the potential exacerbation of mental health issues resulting from cannabis use.

conclusionClinicians are hampered by a lack of clinically relevant information about cannabis use, efficacy and side-effects. Currently no guidelines exist for clinicians to address opioid and cannabis co-use, or to discuss the risk and benefits of cannabis for CNCP management, including side effects. Cannabis and opioid co-use was commonly reported by patients in our sample, yet rarely addressed during clinical CNCP care. Further research is needed on the risks and benefits of cannabis and opioid co-use.

Indexed as

CannabisPatientsPhysiciansAnalgesics, OpioidAttitude of Health PersonnelCannabinoidsChronic PainHumansOpioid-Related DisordersPain ManagementPrimary Health CareSan FranciscoAnalgesics, OpioidCannabinoidsCannabisChronic-painCo-useOpioidsSafety net

Identifiers

PMID30472467
PMCPMC6353665
OpenAlexW2901141418

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.