Evidence map›Paper›PMID 30471956›Full record

ArticleVaccine2019

Prioritization of risk groups for influenza vaccination in resource limited settings - A case study from South Africa.

Meredith L McMorrow, Stefano Tempia, Sibongile Walaza, Florette K Treurnicht, Wayne Ramkrishna, Eduardo Azziz-Baumgartner, Shabir A Madhi, Cheryl Cohen

Registry-linked trialAbstract read
In one paragraph

Article in Vaccine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05996549 (Acceptability, Cost-Effectiveness, and Capacity of a Facility-Based Seasonal Influenza Vaccination), which is not on this map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05996549 phase4unknown statusnot on this mapstarted 2022, after this paper: background citation

Acceptability, Cost-Effectiveness, and Capacity of a Facility-Based Seasonal Influenza Vaccination: A Study in Selected Hospitals of Bangladesh

TypeinterventionalSponsorInternational Centre for Diarrhoeal Disease Research, BangladeshRan2022 to 2024Enrolled2,567ConditionsInfluenza Vaccine, Cost-Effectiveness, VaccinationArmsQuadrivalent Influenza Vaccine
3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Costs of seasonal influenza vaccination in South Africa.Influenza and other respiratory viruses · 2022
    Review
  10. Observational
  11. Multi-period vaccine allocation model in a pandemic: A case study of COVID-19 in Australia.Transportation research. Part E, Logistics and transportation review · 2022
    Article
  12. Article
  13. A decision support system for prioritised COVID-19 two-dosage vaccination allocation and distribution.Transportation research. Part E, Logistics and transportation review · 2022
    Article
  14. Article
  15. Maternal vaccination: A narrative review.Southern African journal of infectious diseases · 2022
    Review
  16. Article
  17. Observational
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Meredith L McMorrowInfluenza Division, Centers for Disease Control and Prevention, Atlanta, GA, United States; Influenza Program, Centers for Disease Control and Prevention, Pretoria, South Africa; U.S. Public Health Service, Rockville, MD, United States. Electronic address: mmcmorrow@cdc.gov.
Stefano TempiaInfluenza Division, Centers for Disease Control and Prevention, Atlanta, GA, United States; Influenza Program, Centers for Disease Control and Prevention, Pretoria, South Africa; Centre for Respiratory Diseases and Meningitis, National Institute for Communicable Diseases of the National Health Laboratory Service, Johannesburg, South Africa. Electronic address: stefanot@nicd.ac.za.
Sibongile WalazaCentre for Respiratory Diseases and Meningitis, National Institute for Communicable Diseases of the National Health Laboratory Service, Johannesburg, South Africa; School of Public Health, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Florette K TreurnichtCentre for Respiratory Diseases and Meningitis, National Institute for Communicable Diseases of the National Health Laboratory Service, Johannesburg, South Africa.
Wayne RamkrishnaCommunicable Disease Cluster, National Department of Health, South Africa.
Eduardo Azziz-BaumgartnerInfluenza Division, Centers for Disease Control and Prevention, Atlanta, GA, United States; U.S. Public Health Service, Rockville, MD, United States.
Shabir A MadhiMedical Research Council, Respiratory and Meningeal Pathogens Research Unit, University of the Witwatersrand, Johannesburg, South Africa; Department of Science and Technology/National Research Foundation: Vaccine Preventable Diseases, University of the Witwatersrand, Johannesburg, South Africa.
Cheryl CohenCentre for Respiratory Diseases and Meningitis, National Institute for Communicable Diseases of the National Health Laboratory Service, Johannesburg, South Africa; School of Public Health, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.

Funding

Research on the Epidemiology,Prevention,Vaccine Effectiveness and Treatment of Influenza and Other Respiratory Viruses in South Africa.09U01IP001048 · IP · NATIONAL HEALTH LABORATORY SERVICE · PI COHEN, CHERYL · 2016 to 2020
$19.9M
Intramural CDC HHS CC999999NCIRD CDC HHS U01 IP001048
6 · The paper itself

Abstract

backgroundDue to competing health priorities, low- and middle-income countries (LMIC) may need to prioritize between different influenza vaccine risk groups. Risk group prioritization may differ in LMIC based upon programmatic feasibility, country-specific prevalence of risk conditions and influenza-associated morbidity and mortality.

methodsIn South Africa, we collected local disease burden data (both published and unpublished) and published vaccine efficacy data in risk groups and healthy adults. We used these data to aid policy makers with risk group prioritization for influenza vaccination. We used the following formula to assess potential vaccine averted disease in each risk group: rate of influenza-associated hospitalization (or death) per 100,000 population * influenza vaccine efficacy (VE). We further estimated the cost per hospital day averted and the cost per year of life saved by influenza vaccination.

resultsPregnant women, HIV-infected adults, and adults and children with tuberculosis disease had among the highest estimates of hospitalizations averted per 100,000 vaccinated and adults aged 65 years and older had the highest estimated deaths averted per 100,000 vaccinated. However, when assessing both the cost per hospital day averted (range: USD148-1,344) and the cost per year of life saved (range: USD112-1,230); adults and children with TB disease, HIV-infected adults and pregnant women had the lowest cost per outcome averted. DISCUSSION: An assessment of the potential disease outcomes averted and associated costs may aid policymakers in risk group prioritization for influenza vaccination.

Indexed as

Health PrioritiesHealth ResourcesAdolescentAdultAgedCase-Control StudiesChildChild, PreschoolCost-Benefit AnalysisCost of IllnessFemaleHIV InfectionsHospitalizationHumansInfantInfluenza, HumanInfluenza VaccinesHospitalizationInfluenzaMortalitySouth AfricaVaccine policy

Identifiers

PMID30471956
PMCPMC6470296

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.