Evidence map›Paper›PMID 30471724›Full record

ReviewPlant science : an international journal of experimental plant biology2019

Mini review: Revisiting mobile RNA silencing in plants.

Xian Zhang, Tongfei Lai, Pengcheng Zhang, Xinlian Zhang, Chen Yuan, Zhenhui Jin, Hongmei Li, Zhiming Yu, Cheng Qin, Mahmut Tör and 3 more

Open access · greenAbstract readReview
In one paragraph

Review in Plant science : an international journal of experimental plant biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
10.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 51 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Spinach-based RNA mimicking GFP in plant cells.Functional & integrative genomics · 2022
    Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Small RNA Profiling of Susceptible and ResistantFrontiers in plant science · 2021
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 3 countries.

Xian ZhangResearch Centre for Plant RNA Signaling, College of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou 310036, China.
Tongfei LaiResearch Centre for Plant RNA Signaling, College of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou 310036, China.
Pengcheng ZhangResearch Centre for Plant RNA Signaling, College of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou 310036, China.
Xinlian ZhangDepartment of Statistics, University of Georgia, Athens, GA 30602, USA.
Chen YuanResearch Centre for Plant RNA Signaling, College of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou 310036, China.
Zhenhui JinResearch Centre for Plant RNA Signaling, College of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou 310036, China.
Hongmei LiResearch Centre for Plant RNA Signaling, College of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou 310036, China.
Zhiming YuResearch Centre for Plant RNA Signaling, College of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou 310036, China.
Cheng QinResearch Centre for Plant RNA Signaling, College of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou 310036, China.
Mahmut TörWorcester-Hangzhou Joint Molecular Plant Health Laboratory, Institute of Science and the Environment, University of Worcester, WR2 6AJ, UK.
Ping MaDepartment of Statistics, University of Georgia, Athens, GA 30602, USA.
Qi ChengNitrogen Fixation Laboratory, Qi Institute, Jiaxing 314000, Zhejiang, China.
Yiguo HongResearch Centre for Plant RNA Signaling, College of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou 310036, China; Worcester-Hangzhou Joint Molecular Plant Health Laboratory, Institute of Science and the Environment, University of Worcester, WR2 6AJ, UK; Warwick-Hangzhou RNA Signaling Joint Laboratory, School of Life Sciences, University of Warwick, Warwick CV4 7AL, UK. Electronic address: yiguo.hong@hznu.edu.cn.
Hangzhou Normal University · CNJiaxing University · CNUniversity of Georgia · USUniversity of Worcester · GB

Funding

Novel statistical tools for cell line specific epigenetic analysisR01GM113242 · NIGMS · UNIVERSITY OF GEORGIA · PI ZHONG, WENXUAN · 2014 to 2017
$1.4M
Deciphering the Regulatory Role of Small RNAs on Alternative Splicing R01GM122080 · NIGMS · UNIVERSITY OF GEORGIA · PI MA, PING · 2016 to 2019
$1.3M
NIGMS NIH HHS R01 GM113242NIGMS NIH HHS R01 GM122080
6 · The paper itself

Abstract

Non-cell autonomous RNA silencing can spread from cell to cell and over long-distances in animals and plants. This process is genetically determined and requires mobile RNA signals. Genetic requirement and molecular nature of the mobile signals for non-cell-autonomous RNA silencing were intensively investigated in past few decades. No consensus dogma for mobile silencing can be reached in plants, yet published data are sometimes inconsistent and controversial. Thus, the genetic requirements and molecular signals involved in plant mobile silencing are still poorly understood. This article revisits our present understanding of intercellular and systemic non-cell autonomous RNA silencing, and summarises current debates on RNA signals for mobile silencing. In particular, we discuss new evidence on siRNA mobility, a DCL2-dependent genetic network for mobile silencing and its potential biological relevance as well as 22 nt siRNA being a mobile signal for non-cell-autonomous silencing in both Arabidopsis and Nicotiana benthamiana. This sets up a new trend in unravelling genetic components and small RNA signal molecules for mobile silencing in (across) plants and other organisms of different kingdoms. Finally we raise several outstanding questions that need to be addressed in future plant silencing research.

Indexed as

Models, GeneticRNA InterferenceCell CommunicationPlantsDICER-LIKEsIntercellular RNA silencingMobile silencing signalSmall interfering RNA (siRNA)Systemic RNA silencing

Identifiers

PMID30471724
PMCPMC6556431
OpenAlexW2898908044

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.