Evidence map›Paper›PMID 30471304›Full record

Trial reportThe Journal of allergy and clinical immunology2019

Vaccination of nonallergic individuals with recombinant hypoallergenic fragments of birch pollen allergen Bet v 1: Safety, effects, and mechanisms.

Raffaela Campana, Katharina Marth, Petra Zieglmayer, Milena Weber, Christian Lupinek, Yury Zhernov, Olga Elisyutina, Musa Khaitov, Eva Rigler, Kerstin Westritschnig and 5 more

Open access · hybridAbstract readLetterRandomized Controlled Trial
In one paragraph

Trial report in The Journal of allergy and clinical immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 34 citations in OpenAlex.

  1. Patient-Derived IgG Epitope Mapping of Bet v 1 Reveals Hypoallergenic Peptide Candidates for Safe and Next-Generation Allergen Immunotherapy.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2026
    Article
  2. Article
  3. Article
  4. Allergen immunotherapy: past, present and future.Nature reviews. Immunology · 2023
    Review
  5. Article
  6. Review
  7. Review
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  10. Article
  11. Article
  12. Review
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  15. Article
  16. Recombinant allergens for immunotherapy: state of the art.Current opinion in allergy and clinical immunology · 2019
    Review
  17. Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 2 countries.

Raffaela CampanaDepartment of Pathophysiology and Allergy Research, Medical University of Vienna, Waehringer Guertel, Vienna, Austria.
Katharina MarthDepartment of Pathophysiology and Allergy Research, Medical University of Vienna, Waehringer Guertel, Vienna, Austria.
Petra ZieglmayerVienna Challenge Chamber, Huetteldorfer Straße, Vienna, Austria.
Milena WeberDepartment of Pathophysiology and Allergy Research, Medical University of Vienna, Waehringer Guertel, Vienna, Austria.
Christian LupinekDepartment of Pathophysiology and Allergy Research, Medical University of Vienna, Waehringer Guertel, Vienna, Austria.
Yury ZhernovNRC Institute of Immunology FMBA of Russia, Moscow, Russia.
Olga ElisyutinaNRC Institute of Immunology FMBA of Russia, Moscow, Russia.
Musa KhaitovNRC Institute of Immunology FMBA of Russia, Moscow, Russia.
Eva RiglerDepartment of Pathophysiology and Allergy Research, Medical University of Vienna, Waehringer Guertel, Vienna, Austria.
Kerstin WestritschnigDepartment of Pathophysiology and Allergy Research, Medical University of Vienna, Waehringer Guertel, Vienna, Austria.
Uwe BergerDepartment of Oto-Rhino-Laryngology, Medical University of Vienna, Vienna, Austria.
Martin WolkersdorferDepartment of Production, Landesapotheke Salzburg, Muellner Hauptstraße, Salzburg, Austria.
Fritz HorakAllergy Center Vienna West, Huetteldorfer Straße, Vienna, Austria.
Friedrich HorakVienna Challenge Chamber, Huetteldorfer Straße, Vienna, Austria; Allergy Center Vienna West, Huetteldorfer Straße, Vienna, Austria.
Rudolf ValentaDepartment of Pathophysiology and Allergy Research, Medical University of Vienna, Waehringer Guertel, Vienna, Austria; NRC Institute of Immunology FMBA of Russia, Moscow, Russia; Laboratory for Immunopathology, Department of Clinical Immunology and Allergy, Sechenov First Moscow State Medical University, Moscow, Russia. Electronic address: Rudolf.valenta@meduniwien.ac.at.
Medical University of Vienna · ATInstitute of Immunology and Physiology · RUVienna Challenge Chamber · ATAllergiezentrum Wien West · ATSalzburger Landeskliniken · AT

Funding

Austrian Science Fund FWF F 4605
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

VaccinationAdolescentAdultAllergensAntigens, PlantBetulaDouble-Blind MethodFemaleHumansImmunoglobulin EImmunoglobulin GMalePollenRecombinant ProteinsRhinitis, Allergic, SeasonalYoung AdultAllergensAntigens, PlantBet v 1 allergen, BetulaImmunoglobulin EImmunoglobulin GRecombinant Proteins

Identifiers

PMID30471304
PMCPMC6411133
OpenAlexW2901651294

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.