ArticleJournal of the American Geriatrics Society2019
Multimorbidity and Mental Health-Related Quality of Life and Risk of Completed Suicide.
Article in Journal of the American Geriatrics Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05264207 (Nursing Students' Visits to Older Adults With Multiple Chronic Conditions), which is not on this map. Cited by 34 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Nursing Students' Visits to Older Adults With Multiple Chronic Conditions: Effects on Self-care and Other Related Variables (VISITAME)
Who cites it
34 citing papers in PubMed, 1 synthesis or guideline pooled it, 62 citations in OpenAlex.
- Pooled it
- Physical Health Conditions Among Suicide Decedents: National Violent Death Reporting System, U.S., 2020-2023.American journal of preventive medicine · 2026Article
- The bidirectional relationships among multimorbidity, depression, and catastrophic health expenditures in middle-aged and older Chinese adults: random-intercept, cross-lagged panel model.BMC public health · 2026Article
- Association between sleep, sunlight exposure, and multimorbidity in older adults with and without mental illness.Frontiers in public health · 2026Article
- Retrospective analysis of multimorbidity, polypharmacy, and drug interactions on postoperative outcomes in oral squamous cell carcinoma patients.Clinical oral investigations · 2025Article
- Impact of early-life food deprivation on health-related quality of life among older people in China: evidence from CHARLS.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025Article
- Capturing the care of complex community-based health center patients: A comparison of multimorbidity indices and clinical classification software.Health services research · 2025Article
- Group Psychological Therapy Program in Adult Patients with Congenital Heart Disease and Anxious-Depressive Symptoms.Medicina (Kaunas, Lithuania) · 2025Article
- Validity of the Chinese multimorbidity-weighted index in measuring disease burden using health check-ups data in primary care.BMC public health · 2024Article
- Observational
- Mental-somatic multimorbidity in trajectories of cognitive function for middle-aged and older adults.PloS one · 2024Article
- Multimorbidity and health-related quality of life amongst Indigenous Australians: A longitudinal analysis.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024Article
- Effects of home visiting programmes on community-dwelling older adults with chronic multimorbidity: a scoping review.BMC nursing · 2023Article
- Multimorbidity, 30-Day Readmissions, and Postdischarge Mortality Among Medicare Beneficiaries Using a New ICD-Coded Multimorbidity-Weighted Index.The journals of gerontology. Series A, Biological sciences and medical sciences · 2023Article
- Physical and mental illness comorbidity among individuals with frequent self-harm episodes: A mixed-methods study.Frontiers in psychiatry · 2023Article
- Research trends in the mental health and multimorbidity of older people from 2002 to 2022: A bibliometric analysisFrontiers in psychiatry · 2023Article
- Multimorbidity and long-term disability and physical functioning decline in middle-aged and older Americans: an observational study.BMC geriatrics · 2022Observational
- Comparing the association between multiple chronic conditions, multimorbidity, frailty, and survival among older patients with cancer.Journal of geriatric oncology · 2022Article
- Main and moderated effects of multimorbidity and depressive symptoms on cognition.Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) · 2022Article
- Multimorbidity and Inpatient Utilization Among Older Adults with Opioid Use Disorder in New York City.Journal of general internal medicine · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundPhysical functioning indexed multimorbidity is strongly associated with long-term mortality, but its role in poor mental health has not been quantified.
methodsA total of 252 002 community-dwelling adults in the Nurses' Health Study (NHS), NHS II, and Health Professionals Follow-up Study (HPFS) prospective cohorts reported physician-diagnosed diseases and the Short Form-36 over 8 years and had 24-year follow-up for suicide mortality. We quantified multimorbidity using a multimorbidity-weighted index (MWI). We used multivariable-adjusted proportional hazards models with competing risks for suicide mortality and mixed-effects models to estimate mental health-related quality of life (HRQOL).
resultsMultimorbidity was associated with an increased risk of suicide mortality in an approximately linear manner, with roughly two- to threefold higher risk in adults with the highest vs lowest quartile MWI in adjusted models: NHS hazard ratio (HR) = 3.01 (95% confidence interval [CI] = 1.48-6.11); NHS II HR = 3.04 (95% CI = 1.82-5.09); HPFS HR = 1.74 (95% CI = 1.08-2.81). Greater MWI was associated with worse mental HRQOL 8 years later across all scales and the mental component summary (MCS) in a dose-response manner. This association was attenuated but persisted after adjustment for baseline mental HRQOL and other covariates. Adults with the highest quartile MWI had lower MCS in adjusted models compared with those with the lowest quartile MWI: NHS ß = -0.61 (95% CI = -0.78 to -0.44); NHS II ß = -1.25 (95% CI = -1.44 to -1.06).
conclusionMultimorbidity is associated with substantially higher suicide mortality risk and worse mental HRQOL across all available scales, even when indexed to physical functioning. These results highlight the substantial mental health burden imposed by multimorbidity at all ages and sexes. J Am Geriatr Soc 67:511-519, 2019.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.