Evidence map›Paper›PMID 30470991›Full record

ArticleClinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico2019

SEOM clinical practice guideline: management and prevention of febrile neutropenia in adults with solid tumors (2018).

A Carmona-Bayonas, P Jimenez-Fonseca, E M de Castro, E Mata, M Biosca, A Custodio, J Espinosa, E G Vázquez, F Henao, F Ayala de la Peña

Open access · hybridAbstract read
In one paragraph

Article in Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

  1. Ambulatory management of low-risk febrile neutropenia in adult oncological patients. Systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
    Pooled it
  2. SEOM-GGCC clinical guidelines for the prophylaxis of infectious diseases in patients with cancer (UPDATE 2026).Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Pathogens (Basel, Switzerland) · 2022
    Review
  11. SEOM clinical guidelines for the prophylaxis of infectious diseases in cancer patients (2021).Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2022
    Article
  12. Article
  13. Article
  14. Review
  15. Common misconceptions in the prognostic evaluation of clinically stable patients with febrile neutropenia and solid tumors.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2019
    Article
  16. SEOM guidelines 2018.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 9 institutions in 1 country.

A Carmona-BayonasHematology and Medical Oncology Department, Hospital Universitario Morales Meseguer, IMIB, Avenida Marqués de los Vélez, 30008, Murcia, Spain.
P Jimenez-FonsecaMedical Oncology Department, Hospital Universitario Central de Asturias, Oviedo, Spain.
E M de CastroMedical Oncology Department, Hospital Universitario Marqués de Valdecilla, Santander, Spain.
E MataMedical Oncology Department, Complejo Hospitalario de Navarra, Pamplona, Spain.
M BioscaMedical Oncology Department, Hospital Vall D'Hebron, Barcelona, Spain.
A CustodioMedical Oncology Department, Hospital Universitario La Paz, Madrid, Spain.
J EspinosaMedical Oncology Department, Hospital General de Ciudad Real, Ciudad Real, Spain.
E G VázquezInfectious Disease Department, Hospital Universitario Virgen de la Arrixaca, Murcia, Spain.
F HenaoMedical Oncology Department, Complejo Hospitalario Regional Virgen Macarena, Seville, Spain.
F Ayala de la PeñaHematology and Medical Oncology Department, Hospital Universitario Morales Meseguer, IMIB, Avenida Marqués de los Vélez, 30008, Murcia, Spain. frayala@um.es.ORCID http://orcid.org/0000-0001-6311-920X
Hospital General Universitario Morales Meseguer · ESComplejo Hospitalario de Navarra · ESHospital General Universitario de Ciudad Real · ESHospital Universitario Central de Asturias · ESHospital Universitario La Paz · ESHospital Universitario Virgen de la Arrixaca · ESHospital Universitario Virgen Macarena · ESMarqués de Valdecilla University Hospital · ESVall d'Hebron Hospital Universitari · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Febrile neutropenia (FN) is a common dose-limiting toxicity of chemotherapy, with a profound impact on the evolution of patients with cancer, due to the potential development of serious complications, mortality, delays, and decrease in treatment intensity. This article seeks to present an updated clinical guideline, with recommendations regarding the diagnosis, prevention, and treatment of febrile neutropenia in adults with solid tumors. The aspects covered include how to properly approach the risk of microbial resistances, epidemiological aspects, considerations about the initial empirical approach adapted to the risk, special situations, and prevention of complications. A decision-making algorithm is included for use in the emergency department based on a new, validated tool, the Clinical Index of Stable Febrile Neutropenia, which can be used in patients with solid tumors who appear stable in the initial phase of neutropenic infections, and can help detect those at high risk for complications in whom early discharge must be avoided.

Indexed as

Severity of Illness IndexAdultAntineoplastic AgentsClinical Trials as TopicDisease ManagementFebrile NeutropeniaGranulocyte Colony-Stimulating FactorHumansNeoplasmsPractice Guidelines as TopicPrognosisRisk AssessmentSocieties, MedicalAntineoplastic AgentsGranulocyte Colony-Stimulating FactorCISNE scoreClinical practice guidelineFebrile neutropeniaSEOM

Identifiers

PMID30470991
PMCPMC6339667
OpenAlexW2900936942

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.