Evidence map›Paper›PMID 30470970›Full record

ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2019

Association between medication adherence and quality of life of patients with diabetes and hypertension attending primary care clinics: a cross-sectional survey.

Sarah M Khayyat, Mahmoud M A Mohamed, Salwa M Saeed Khayyat, Raghda S Hyat Alhazmi, Mulham Fouad Korani, Ebtesam Bakheet Allugmani, Sarah Fathallah Saleh, Deyaa Abdulla Mansouri, Qasim A Lamfon, Osama Mohammed Beshiri and 1 more

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Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

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49citing papers in PubMed
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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

49 citing papers in PubMed.

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  10. Factors Affecting Medication Adherence in Middle-Aged and Elderly Patients in China: A Cross-Sectional Study.Medical science monitor : international medical journal of experimental and clinical research · 2025
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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Sarah M KhayyatDepartment of Clinical Pharmacy, Faculty of Pharmacy, Umm Al-Qura University, Makkah, Saudi Arabia. smkhayat@uqu.edu.sa.ORCID http://orcid.org/0000-0002-0316-1825
Mahmoud M A MohamedBerlin-Brandenburg Centre for Regenerative Therapies, Charite Universitatsmedizin Berlin, Berlin, Germany.
Salwa M Saeed KhayyatJoint Program of Family Medicine, Ministry of Health, Makkah, Saudi Arabia.
Raghda S Hyat AlhazmiPublic Health Centres, Ministry of Health, Makkah, Saudi Arabia.
Mulham Fouad KoraniJoint Program of Family Medicine, Ministry of Health, Makkah, Saudi Arabia.
Ebtesam Bakheet AllugmaniJoint Program of Family Medicine, Ministry of Health, Makkah, Saudi Arabia.
Sarah Fathallah SalehJoint Program of Family Medicine, Ministry of Health, Makkah, Saudi Arabia.
Deyaa Abdulla MansouriPublic Health Centres, Ministry of Health, Makkah, Saudi Arabia.
Qasim A LamfonJoint Program of Family Medicine, Ministry of Health, Makkah, Saudi Arabia.
Osama Mohammed BeshiriPublic Health Centres, Ministry of Health, Makkah, Saudi Arabia.
Muhammad Abdul HadiSchool of Pharmacy, Institute of Clinical Sciences, University of Birmingham, Birmingham, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the association between medication adherence and quality of life (QoL) of patients with diabetes and/or hypertension attending primary care clinics.

methodsIn this cross-sectional study, patients with at least one long-term condition (hypertension or diabetes mellitus) meeting the eligibility criteria were recruited from five primary care clinics in Saudi Arabia. Arabic version of Morisky Medication Adherence Scale (MMAS-8) and the World Health Organization Quality of Life-BREF (WHOQOL-BREF) tool were used to assess medication adherence and QoL, respectively. Patients' sociodemographic, medical and medication data were collected using a structured, pilot-tested data collection form.

resultsThree hundred patients with a mean (± SD) age of 56.79 (12.8) years participated in the study. Fifty-eight had hypertension only, 96 had diabetes (Type 1 or 2), and 146 had both hypertension and diabetes. After adjusting for socioeconomic characteristics, multiple linear regression analysis found that adherent patients had significantly higher mean overall perception of QoL and health scores by 14.6 (P = 0.001) and 17.2 (P = 0.001) points, respectively, compared to non-adherent patients. In addition, irrespective of the type of long-term condition, adherence status was found to be an independent predictor of all QoL domains.

conclusionThere is an association between medication adherence and QoL among patients with diabetes and/or hypertension attending primary care clinics. Medication adherence should be assessed and emphasised during routine clinical consultations in primary care in order to achieve the desired clinical outcomes and overall well-being of patients.

Indexed as

Cross-Sectional StudiesDiabetes MellitusFemaleHumansHypertensionMaleMedication AdherenceMiddle AgedPrimary Health CareQuality of LifeSurveys and QuestionnairesComplianceDiabetes mellitusHypertensionMedication adherencePrimary careQuality of life

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.