ArticleJournal of patient-reported outcomes2018
Depressive symptom prevalence after intracerebral hemorrhage: a multi-center study.
Article in Journal of patient-reported outcomes, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.
- Prevalence, Trajectory, and Factors Associated With Patient-Reported Nonmotor Outcomes After Stroke: A Systematic Review and Meta-Analysis.JAMA network open · 2025Pooled it
- Lactylation and N6-Methyladenosine RNA modification in neuropsychiatric sequelae after intracerebral hemorrhage: a hypothesis-generating metabolic-glial-circuit framework.Molecular biology reports · 2026Review
- Short form scale of parent self-efficacy for general and specialized care for children with special health care needs.Journal of patient-reported outcomes · 2026Article
- Serum prealbumin at admission is associated with post-stroke depression at 3 months in patients with spontaneous intracerebral hemorrhage.Frontiers in psychiatry · 2026Article
- How to Cope with Coping in Adult Post-Hemorrhagic Patients Undergoing Neurorehabilitation: A Scoping Review.Journal of clinical medicine · 2025Review
- Depression in Patients With Intracranial Hemorrhage Secondary to Traumatic Brain Injury.Cureus · 2023Article
- Parental self-efficacy managing a child's medications and treatments: adaptation of a PROMIS measure.Journal of patient-reported outcomes · 2023Article
- Depression and the Use of Selective Serotonin Reuptake Inhibitors in Patients with Acute Intracerebral Hemorrhage.Cureus · 2019Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
introductionDepressive symptoms in patients with intracerebral hemorrhage (ICH) are common and are associated with worse outcomes. It is not well described how often depressive symptoms are ascertained and treated in large unselected cohorts of patients, and whether depressive symptoms would be a potential target for improving outcomes.
methodsData were electronically retrieved from a multi-center EHR repository in Chicago, IL, from 2006 to 2012 ("multicenter cohort"). In the multicenter cohort, we retrieved diagnostic codes and medication data from four university health systems across Chicago. In the single center cohort, we prospectively screened for depressive symptoms (NIH Patient Reported Outcomes Measurement Information System, PROMIS, T Score ≥ 60), at one, three and twelve months after ICH onset. It should be noted that not all depressive symptoms are optimally characterized through diagnostic codes.
resultsDiagnostic codes for depressive symptoms up to three months after ICH onset were recorded in 132 of 3422 (3.8%) of the multicenter cohort; fewer than 10% of patients received a typical medication to treat depressive symptoms, and < 2% one month later. In the single-center cohort, PROMIS assessments were indicative of depressive symptoms in 26 of 116 (22.4%), and depressive symptoms were more likely to be found with screening (OR 7.20, 95% CI 4.5-11.5, P < 0.0001). Results were similar up to 12 months after ICH.
conclusionsDepressive symptoms in patients with ICH are more common than medication treatment or a coded diagnosis in a multi-center cohort, and are a potential opportunity for additional treatment to improve outcomes. There are currently no AHA/ASA treatment guidelines for depression screening of patients with ICH.
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