Evidence map›Paper›PMID 30470804›Full record

Trial reportInternational journal of obesity (2005)2019

Effect of intermittent compared to continuous energy restriction on weight loss and weight maintenance after 12 months in healthy overweight or obese adults.

Michelle Louise Headland, Peter Marshall Clifton, Jennifer Beatrice Keogh

Erratum issuedAbstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in International journal of obesity (2005), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 51 papers, 14 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed, 14 pooled it
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 14 syntheses or guidelines pooled it, 99 citations in OpenAlex.

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  12. Intermittent fasting for the prevention of cardiovascular disease.The Cochrane database of systematic reviews · 2021
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  13. Intermittent fasting and weight loss: Systematic review.Canadian family physician Medecin de famille canadien · 2020
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Michelle Louise HeadlandDivision of Health Sciences, School of Pharmacy and Medical Sciences, University of South Australia, Adelaide, SA, Australia.
Peter Marshall CliftonDivision of Health Sciences, School of Pharmacy and Medical Sciences, University of South Australia, Adelaide, SA, Australia.
Jennifer Beatrice KeoghDivision of Health Sciences, School of Pharmacy and Medical Sciences, University of South Australia, Adelaide, SA, Australia. jennifer.keogh@unisa.edu.au.
University of South Australia · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectiveIntermittent energy restriction (IER) is an alternative to continuous energy restriction (CER) for weight loss. There are few long-term trials comparing efficacy of these methods. The objective was to compare the effects of CER to two forms of IER; a week-on-week-off energy restriction and a 5:2 program, during which participants restricted their energy intake severely for 2 days and ate as usual for 5 days, on weight loss, body composition, blood lipids, and glucose. SUBJECTS AND

methodsA one-year randomized parallel trial was conducted at the University of South Australia, Adelaide, Australia. Participants were 332 overweight and obese adults, ages 18-72 years, who were randomized to 1 of 3 groups: CER (4200 kJ/day for women and 5040 kJ/day for men), week-on-week-off energy restriction (alternating between the same energy restriction as the continuous group for one week and one week of habitual diet), or 5:2 (2100 kJ/day on modified fast days each week for women and 2520 kJ/day for men, the 2 days of energy restriction could be consecutive or non-consecutive). Primary outcome was weight loss, and secondary outcomes were changes in body composition, blood lipids, and glucose.

resultsFor the 146 individuals who completed the study (124 female, 22 male, mean BMI 33 kg/m DISCUSSION AND

conclusionThe two forms of IER were not statistically different for weight loss, body composition, and cardiometabolic risk factors compared to CER.

Indexed as

AdultAgedAustraliaBody Weight MaintenanceCaloric RestrictionDiet, ReducingEnergy IntakeFemaleHumansMaleMiddle AgedObesityOverweightPatient ComplianceRetrospective StudiesTime Factors

Identifiers

PMID30470804
OpenAlexW2900627638

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.