ArticleCell research2018
Cryo-EM reveals ligand induced allostery underlying InsP
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Article in Cell research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
37 citing papers in PubMed, 58 citations in OpenAlex.
- Cryo-EM insights into isoform-specific properties of the IPNature communications · 2026Article
- Conformational landscape and ligand-dependent clustering of the human type 2 IPNature communications · 2026Article
- Conformational landscape and clustering of human type 2 IPbioRxiv : the preprint server for biology · 2026Article
- The Evolving Landscape of Protein Allostery: From Computational and Experimental Perspectives.Journal of molecular biology · 2025Review
- LIPUS Promotes Calcium Oscillation and Enhances Calcium Dependent Autophagy of Chondrocytes to Alleviate Osteoarthritis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Dominant negative variants in ITPR3 impair T cell Ca2+ dynamics causing combined immunodeficiency.The Journal of experimental medicine · 2025Article
- Dissecting the neuroprotective interaction between the BH4 domain of BCL-w and the IP3 receptor.Cell chemical biology · 2024Article
- Type 3 IP3 receptor: Its structure, functions, and related disease implications.Channels (Austin, Tex.) · 2023Review
- Structural titration reveals CaNature communications · 2023Article
- Understanding IPCell calcium · 2023Review
- Redox states in the endoplasmic reticulum directly regulate the activity of calcium channel, inositol 1,4,5-trisphosphate receptors.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Ligand sensitivity of type-1 inositol 1,4,5-trisphosphate receptor is enhanced by the D2594K mutation.Pflugers Archiv : European journal of physiology · 2023Article
- Disrupted CaCellular & molecular immunology · 2023Article
- Missense mutations in inositol 1,4,5-trisphosphate receptor type 3 result in leaky CaiScience · 2022Article
- Conformational motions and ligand-binding underlying gating and regulation in IPNature communications · 2022Article
- Functional determination of calcium-binding sites required for the activation of inositol 1,4,5-trisphosphate receptors.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Beyond the Backbone: The Next Generation of Pathwalking Utilities for Model Building in CryoEM Density Maps.Biomolecules · 2022Article
- Binding of the erlin1/2 complex to the third intralumenal loop of IPThe Journal of biological chemistry · 2022Article
- Structural basis for activation and gating of IPNature communications · 2022Article
- Combined Pharmacophore and Grid-Independent Molecular Descriptors (GRIND) Analysis to Probe 3D Features of Inositol 1,4,5-Trisphosphate Receptor (IPInternational journal of molecular sciences · 2021Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Guizhen FanDepartment of Biochemistry and Molecular Biology, Structural Biology Imaging Center, McGovern Medical School at The University of Texas Health Science Center at Houston, 6431 Fannin Street, Houston, TX, 77030, USA.
Mariah R BakerDepartment of Biochemistry and Molecular Biology, Structural Biology Imaging Center, McGovern Medical School at The University of Texas Health Science Center at Houston, 6431 Fannin Street, Houston, TX, 77030, USA.
Zhao WangVerna and Marrs McLean Department of Biochemistry and Molecular Biology, CryoEM and CryoET Core, Baylor College of Medicine, One Baylor Plaza, Houston, TX, 77030, USA.
Alexander B SeryshevDepartment of Biochemistry and Molecular Biology, Structural Biology Imaging Center, McGovern Medical School at The University of Texas Health Science Center at Houston, 6431 Fannin Street, Houston, TX, 77030, USA.
Steven J LudtkeVerna and Marrs McLean Department of Biochemistry and Molecular Biology, CryoEM and CryoET Core, Baylor College of Medicine, One Baylor Plaza, Houston, TX, 77030, USA.
Matthew L BakerVerna and Marrs McLean Department of Biochemistry and Molecular Biology, CryoEM and CryoET Core, Baylor College of Medicine, One Baylor Plaza, Houston, TX, 77030, USA.
Irina I SeryshevaDepartment of Biochemistry and Molecular Biology, Structural Biology Imaging Center, McGovern Medical School at The University of Texas Health Science Center at Houston, 6431 Fannin Street, Houston, TX, 77030, USA. irina.i.serysheva@uth.tmc.edu.
Baylor College of Medicine · USImaging Center · USThe University of Texas Health Science Center at Houston · US
Funding
3 D ELECTRON MICROSCOPY OF MACROMOLECULES (5P41RR002250-27)P41GM103832 · NIGMS · STANFORD UNIVERSITY · PI CHIU, WAH · 2012 to 2019
$15.1MSUPPORT AND DEVELOPMENT OF EMAN FOR ELECTRON MICROSCOPY IMAGE PROCESSINGR01GM080139 · NIGMS · BAYLOR COLLEGE OF MEDICINE · PI LUDTKE, STEVEN J · 2006 to 2022
$5.4MStructure-Function Studies Of IP3R ChannelsR01GM072804 · NIGMS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI SERYSHEVA, IRINA I · 2005 to 2023
$4.8MRegulation of IP3R channel in apoptosisR21NS106968 · NINDS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI SERYSHEVA, IRINA I · 2018 to 2019
$424kStructural Studies of RyR ChannelR21AR063255 · NIAMS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI SERYSHEVA, IRINA I · 2013 to 2014
$368kNIAMS NIH HHS R21 AR063255NIGMS NIH HHS P41 GM103832NIGMS NIH HHS R01 GM072804NIGMS NIH HHS R01 GM080139NINDS NIH HHS R21 NS106968
Abstract
Inositol-1,4,5-trisphosphate receptors (InsP
Indexed as
Calcium SignalingIon Channel GatingProtein ConformationAdenosineAllosteric RegulationAnimalsCalciumCerebellumCryoelectron MicroscopyInositol 1,4,5-Trisphosphate ReceptorsLigandsModels, MolecularRatsadenophostin AAdenosineCalciumInositol 1,4,5-Trisphosphate ReceptorsLigands
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Read underepoch 390
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.