ArticleNature communications2018
Entropy production rate is maximized in non-contractile actomyosin.
Article in Nature communications, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 70 citations in OpenAlex.
- State-dependent energy conversion produces degenerate dissipation in active actomyosin networks.bioRxiv : the preprint server for biology · 2026Article
- Filament transport supports contractile steady states of actin networks.bioRxiv : the preprint server for biology · 2025Article
- Entropy Production in a System of Janus Particles.Entropy (Basel, Switzerland) · 2025Article
- F-actin architecture determines the conversion of chemical energy into mechanical work.Nature communications · 2024Article
- Measuring response functions of active materials from data.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Dissipation and energy propagation across scales in an active cytoskeletal material.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Bioinspired Membrane Interfaces: Controlling Actomyosin Architecture and Contractility.ACS applied materials & interfaces · 2023Article
- Toward droplets displaying life-like interaction behaviors.Biomicrofluidics · 2023Article
- F-actin architecture determines constraints on myosin thick filament motion.Nature communications · 2022Article
- Actin-microtubule dynamic composite forms responsive active matter with memory.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Reconstitution of Membrane-tethered Minimal Actin Cortices on Supported Lipid Bilayers.Journal of visualized experiments : JoVE · 2022Article
- Droplets in underlying chemical communication recreate cell interaction behaviors.Nature communications · 2022Article
- Understanding cytoskeletal avalanches using mechanical stability analysis.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Microfluidic investigation of the effect of graphene oxide on mechanical properties of cell and actin cytoskeleton networks: experimental and theoretical approaches.Scientific reports · 2021Article
- Irreversibility in dynamical phases and transitions.Nature communications · 2021Article
- Learning the non-equilibrium dynamics of Brownian movies.Nature communications · 2020Article
- Myosin II Filament Dynamics in Actin Networks Revealed with Interferometric Scattering Microscopy.Biophysical journal · 2020Article
- The Actin Cytoskeleton as an Active Adaptive Material.Annual review of condensed matter physics · 2020Article
- Quantifying dissipation in actomyosin networks.Interface focus · 2019Article
- Cell-Matrix Elastocapillary Interactions Drive Pressure-based Wetting of Cell Aggregates.Physical review. XArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 4 institutions in 3 countries.
Funding
Abstract
The actin cytoskeleton is an active semi-flexible polymer network whose non-equilibrium properties coordinate both stable and contractile behaviors to maintain or change cell shape. While myosin motors drive the actin cytoskeleton out-of-equilibrium, the role of myosin-driven active stresses in the accumulation and dissipation of mechanical energy is unclear. To investigate this, we synthesize an actomyosin material in vitro whose active stress content can tune the network from stable to contractile. Each increment in activity determines a characteristic spectrum of actin filament fluctuations which is used to calculate the total mechanical work and the production of entropy in the material. We find that the balance of work and entropy does not increase monotonically and the entropy production rate is maximized in the non-contractile, stable state of actomyosin. Our study provides evidence that the origins of entropy production and activity-dependent dissipation relate to disorder in the molecular interactions between actin and myosin.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.