ArticleNature communications2018
Studies into the mechanism of measles-associated immune suppression during a measles outbreak in the Netherlands.
Article in Nature communications, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 67 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Unravelling the Measles Paradox in Children: a Disease Associated With Both Immune Suppression and Immune Activation
Unravelling the Measles Paradox: a Disease Associated With Both Immune Suppression and Immune Activation
Who cites it
67 citing papers in PubMed, 121 citations in OpenAlex.
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- Comprehensive mapping of human CD4Cell reports. Medicine · 2026Article
- Human neutralizing antibodies targeting the measles virus hemagglutinin and fusion surface proteins.Cell host & microbe · 2026Article
- Three paradoxical paradigms of measles virus.PLoS pathogens · 2026Article
- RIG-I Stimulation Enhances the Effector Function and Proliferation of Primary Human CD8+ T Cells.International journal of molecular sciences · 2026Article
- Measles: An Updated Literature Review of the Host Response, Pathogenesis, Complications, Prevention Measures, and Recent Outbreaks.Current issues in molecular biology · 2026Review
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- Measles virus reprograms CD4Frontiers in cell and developmental biology · 2026Article
- Epidemiology, clinical overview, and potential risk of a new pandemic of measles virus.Infectious diseases & immunity · 2025Review
- Measles outbreaks in the United States in 2025: Practice, policy, and the canary in the coalmine.New microbes and new infections · 2025Article
- Article
- Impact of genotypic variability of measles virus T-cell epitopes on vaccine-induced T-cell immunity.NPJ vaccines · 2025Article
- The measles virus matrix F50S mutation from a lethal case of subacute sclerosing panencephalitis promotes receptor-independent neuronal spread.Journal of virology · 2025Article
- Hepatitis B Vaccine Nonresponse and Associated Risk Factors: Insights From a Cohort Study.Journal of tropical medicine · 2025Article
- Cerebral thrombophlebitis observed in a 10-year-old child with measles: A case report.IDCases · 2025Article
- Investigating immune amnesia after measles virus infection in two West African countries: A study protocol.PloS one · 2025Article
- What's going on with measles?Journal of virology · 2024Review
- Immunological landscape of human lymphoid explants during measles virus infection.JCI insight · 2024Article
- Viruses and thrombocytopenia.Heliyon · 2024Review
- Rational attenuation of canine distemper virus (CDV) to develop a morbillivirus animal model that mimics measles in humans.Journal of virology · 2024Article
7 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Measles causes a transient immune suppression, leading to increased susceptibility to opportunistic infections. In experimentally infected non-human primates (NHPs) measles virus (MV) infects and depletes pre-existing memory lymphocytes, causing immune amnesia. A measles outbreak in the Dutch Orthodox Protestant community provided a unique opportunity to study the pathogenesis of measles immune suppression in unvaccinated children. In peripheral blood mononuclear cells (PBMC) of prodromal measles patients, we detected MV-infected memory CD4
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.