Evidence map›Paper›PMID 30470716›Full record

ArticleThe Journal of general physiology2018

A bilobal model of Ca

Worawan B Limpitikul, Joseph L Greenstein, David T Yue, Ivy E Dick, Raimond L Winslow

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of general physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. The mechanism of LQTS related CaM mutation E141G interfering with CaJournal of physiology and biochemistry · 2025
    Article
  3. Article
  4. Calmodulin Mutations in Human Disease.Channels (Austin, Tex.) · 2023
    Review
  5. Regulation of Cardiac Cav1.2 Channels by Calmodulin.International journal of molecular sciences · 2023
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Worawan B LimpitikulCalcium Signals Laboratory, Department of Biomedical Engineering, The Johns Hopkins University School of Medicine, Baltimore, MD.
Joseph L GreensteinInstitute for Computational Medicine, Department of Biomedical Engineering, The Johns Hopkins University, Baltimore, MD.ORCID 0000-0002-6193-7134
David T YueCalcium Signals Laboratory, Department of Biomedical Engineering, The Johns Hopkins University School of Medicine, Baltimore, MD.
Ivy E DickCalcium Signals Laboratory, Department of Biomedical Engineering, The Johns Hopkins University School of Medicine, Baltimore, MD ied@som.umaryland.edu.ORCID 0000-0002-7253-6846
Raimond L WinslowInstitute for Computational Medicine, Department of Biomedical Engineering, The Johns Hopkins University, Baltimore, MD rwinslow@jhu.edu.ORCID 0000-0003-1719-1651
Johns Hopkins University · USUniversity of Maryland, Baltimore · US

Funding

Ca Regulation of Ca ChannelsR01MH065531 · NIMH · JOHNS HOPKINS UNIVERSITY · PI JOHNY, MANU BEN · 2002 to 2016
$5.7M
Calcium Entrained ArrhythmiasR01HL105239 · NHLBI · UNIVERSITY OF MARYLAND BALTIMORE · PI JAFRI, MOHSIN SALEET, LEDERER, WILLIAM JONATHAN · 2011 to 2015
$4.9M
NHLBI NIH HHS R01 HL105239NIMH NIH HHS R01 MH065531
6 · The paper itself

Abstract

L-type calcium channels (LTCCs) are critical elements of normal cardiac function, playing a major role in orchestrating cardiac electrical activity and initiating downstream signaling processes. LTCCs thus use feedback mechanisms to precisely control calcium (Ca

Indexed as

Models, ChemicalCalciumCalcium Channels, L-TypeCalmodulinHumansLong QT SyndromeCalciumCalcium Channels, L-TypeCalmodulin

Identifiers

PMID30470716
PMCPMC6279366
OpenAlexW2900787217

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.