Evidence map›Paper›PMID 30470703›Full record

ArticleDevelopment (Cambridge, England)2018

Conserved regulatory state expression controlled by divergent developmental gene regulatory networks in echinoids.

Eric M Erkenbrack, Eric H Davidson, Isabelle S Peter

Open access · bronzeAbstract read
In one paragraph

Article in Development (Cambridge, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 33 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Eric M ErkenbrackDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA eric.erkenbrack@yale.edu ipeter@caltech.edu.ORCID 0000-0001-9375-3279
Eric H DavidsonDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
Isabelle S PeterDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA eric.erkenbrack@yale.edu ipeter@caltech.edu.ORCID 0000-0003-3685-3147
California Institute of Technology · US

Funding

Transcriptional Casualty in Embryonic Morphogenesis: from the Specifications GRNP01HD037105 · NICHD · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI DAVIDSON, ERIC H · 1999 to 2018
$27.1M
NICHD NIH HHS P01 HD037105
6 · The paper itself

Abstract

Evolution of the animal body plan is driven by changes in developmental gene regulatory networks (GRNs), but how networks change to control novel developmental phenotypes remains, in most cases, unresolved. Here, we address GRN evolution by comparing the endomesoderm GRN in two echinoid sea urchins,

Indexed as

Gene Expression Regulation, DevelopmentalGene Regulatory NetworksAnimalsCell LineageEmbryo, NonmammalianEndodermFeedback, PhysiologicalGastrulationMesodermSea UrchinsSignal TransductionEchinodermsEmbryogenesisGRN evolutionRegulatory statesSubcircuits

Identifiers

PMID30470703
PMCPMC6307887
OpenAlexW2901448356

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.