Evidence map›Paper›PMID 30469316›Full record

ArticleInternational journal of molecular sciences2018

Anti-inflammatory and Neuroprotective Effects of Fungal Immunomodulatory Protein Involving Microglial Inhibition.

Wen-Ying Chen, Cheng-Yi Chang, Jian-Ri Li, Jiaan-Der Wang, Chih-Cheng Wu, Yu-Hsiang Kuan, Su-Lan Liao, Wen-Yi Wang, Chun-Jung Chen

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
4.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. The Biological Activity ofMolecules (Basel, Switzerland) · 2024
    Review
  5. Article
  6. Article
  7. Effects of Alcohol Extracts FromFrontiers in nutrition · 2022
    Article
  8. Article
  9. GMI, an Immunomodulatory Peptide fromInternational journal of molecular sciences · 2021
    Article
  10. Article
  11. Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 7 institutions in 1 country.

Wen-Ying ChenDepartment of Veterinary Medicine, National Chung Hsing University, Taichung 402, Taiwan. wychen@dragon.nchu.edu.tw.
Cheng-Yi ChangDepartment of Surgery, Feng Yuan Hospital, Taichung 402, Taiwan. c.y.chang.ns@gmail.com.
Jian-Ri LiDivision of Urology, Taichung Veterans General Hospital, Taichung 407, Taiwan. fisherfishli@yahoo.com.tw.
Jiaan-Der WangDepartment of Pediatrics & Child Health Care, Taichung Veterans General Hospital, Taichung 407, Taiwan. wangjiaander@gmail.com.ORCID 0000-0002-7908-4969
Chih-Cheng WuDepartment of Anesthesiology, Taichung Veterans General Hospital, Taichung 407, Taiwan. chihcheng.wu@gmail.com.
Yu-Hsiang KuanDepartment of Pharmacology, Chung Shan Medical University, Taichung 402, Taiwan. kuanyh001@gmail.com.
Su-Lan LiaoDepartment of Medical Research, Taichung Veterans General Hospital, Taichung 407, Taiwan. slliao@vghtc.gov.tw.
Wen-Yi WangDepartment of Nursing, Hung Kuang University, Taichung 433, Taiwan. walice@sunrise.hk.edu.tw.
Chun-Jung ChenDepartment of Medical Research, Taichung Veterans General Hospital, Taichung 407, Taiwan. cjchen@vghtc.gov.tw.
Taichung Veterans General Hospital · TWChina Medical University · TWChung Shan Medical University · TWHungkuang University · TWNational Chung Hsing University · TWProvidence University · TWTaichung Hospital · TW

Funding

Ministry of Science and Technology NSC 94-2311-B-075A-001Taichung Veterans General Hospital and Hung Kuang University TCVGH-HK1028003
6 · The paper itself

Abstract

Microglia polarization of classical activation state is crucial to the induction of neuroinflammation, and has been implicated in the pathogenesis of numerous neurodegenerative diseases. Fungal immunomodulatory proteins are emerging health-promoting natural substances with multiple pharmacological activities, including immunomodulation. Herein, we investigated the anti-inflammatory and neuroprotective potential of fungal immunomodulatory protein extracted from

Indexed as

AnimalsAnti-Inflammatory AgentsCells, CulturedFungal ProteinsGanodermaMicrogliaNeuronsNeuroprotective AgentsRatsRats, Sprague-DawleyAnti-Inflammatory AgentsFungal ProteinsNeuroprotective Agentsimmunomodulatory proteinmicroglianeuroinflammationpolarization

Identifiers

PMID30469316
PMCPMC6274830
OpenAlexW2900965093

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.