Evidence map›Paper›PMID 30468392›Full record

ArticlePsychology, health & medicine2019

Adjustment to acute or early HIV-1 infection diagnosis to prompt linkage to care and ART initiation: qualitative insights from coastal Kenya.

E M Van Der Elst, B Kombo, P Mugo, A Thiong'o, J Kanungi, E Wahome, O Chirro, S M Graham, D Operario, E J Sanders

Abstract read
In one paragraph

Article in Psychology, health & medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Significance of initiating antiretroviral therapy in the early stage of HIV infection.Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2022
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

E M Van Der Elsta Kenya Medical Research Institute-Wellcome Trust Research Programme , Kilifi , Kenya.
B Komboa Kenya Medical Research Institute-Wellcome Trust Research Programme , Kilifi , Kenya.
P Mugoa Kenya Medical Research Institute-Wellcome Trust Research Programme , Kilifi , Kenya.
A Thiong'oa Kenya Medical Research Institute-Wellcome Trust Research Programme , Kilifi , Kenya.
J Kanungia Kenya Medical Research Institute-Wellcome Trust Research Programme , Kilifi , Kenya.
E Wahomea Kenya Medical Research Institute-Wellcome Trust Research Programme , Kilifi , Kenya.
O Chirroa Kenya Medical Research Institute-Wellcome Trust Research Programme , Kilifi , Kenya.
S M Grahama Kenya Medical Research Institute-Wellcome Trust Research Programme , Kilifi , Kenya.ORCID 0000-0001-7847-8686
D Operariod Department of Behaviour and Social Sciences , Brown University School of Public Health , RI , USA.
E J Sandersa Kenya Medical Research Institute-Wellcome Trust Research Programme , Kilifi , Kenya.

Funding

Impact of a novel screening program to detect acute and prevalent HIV infection and reduce HIV transmissionR01AI124968 · NIAID · UNIVERSITY OF WASHINGTON · PI GRAHAM, SUSAN MARIE, SANDERS, EDUARD · 2016 to 2019
$2.3M
NIAID NIH HHS R01 AI124968Wellcome TrustWellcome Trust 203077/Z/16/Z
6 · The paper itself

Abstract

Diagnosing and treating patients with acute or early HIV-1 infection (AEHI) is an important strategy to prevent HIV-1 transmission. We used qualitative methods to understand factors that facilitate adjustment to AEHI diagnosis, prompt linkage to care and initiation of antiretroviral treatment (ART). Twenty-three AEHI patients (12 women, 11 men) included 18 participants identified at health facilities, and 5 participants identified in a sex worker cohort. Of these, 17 participants (9 women, 8 men) participated in qualitative interviews about their AEHI status 2 weeks after diagnosis. Thirteen participants (7 women, 6 men) returned for a second interview 12 weeks after diagnosis. Interviews explored participants' experiences at the time of and following their diagnosis, and examined perceptions about ART initiation and behavior change recommendations, including disclosure and partner notification. A grounded theory framework was used for analysis, eliciting three important needs that should be addressed for AEHI patients: 1) the need to better understand AEHI and accept one's status; 2) the need to develop healthy strategies and adjust to the reality of AEHI status; and 3) the need to protect self and others through ART initiation, adherence, safer sex, and disclosure. A preliminary conceptual framework to guide further intervention and research with AEHI populations is proposed.

Indexed as

Emotional AdjustmentAdultAnti-Retroviral AgentsCohort StudiesContact TracingDisclosureEarly DiagnosisFemaleGrounded TheoryHIV-1HIV InfectionsHumansKenyaMaleQualitative ResearchSex WorkersAnti-Retroviral AgentsAcute and early HIV-1 infectionbehavioral adjustmentearly ART initiationKenyalinkage to care

Identifiers

PMID30468392
PMCPMC6425912

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.