ArticleClinical and translational science2019
Psychological and Genetic Predictors of Pain Tolerance.
Article in Clinical and translational science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 27 citations in OpenAlex.
- The impact of different music genres on pain tolerance: emphasizing the significance of individual music genre preferences.Scientific reports · 2024Trial
- Psychophysical predictors of experimental muscle pain intensity following fatiguing calf exercise.PloS one · 2021Trial
- Does individual pain threshold influence postoperative pain after connective tissue graft surgery?Clinical oral investigations · 2026Article
- One in three reports pain in a given week: a one-season prospective study on prevalence of pain and analgesic use in amateur female and male football players.BMJ open sport & exercise medicine · 2026Article
- Experimental pain tolerance is associated with dental anxiety- the Tromsø study 2015-2016.BMC oral health · 2025Article
- Self-assessed threshold for cold temperatures and thermal insulation of clothing among poultry workers.Scientific reports · 2024Article
- Article
- Determinants of satisfaction with acute pain therapy during and after childbirth.Die Anaesthesiologie · 2023Article
- Article
- Evaluation by Survival Analysis of Cold Pain Tolerance in Patients with Fibromyalgia and Opioid Use.Journal of pain research · 2022Article
- More Insight on the Role of Personality Traits and Sensitivity to Experimental Pain.Journal of pain research · 2021Article
- Pain Processing in Elite and High-Level Athletes Compared to Non-athletes.Frontiers in psychology · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 4 institutions in 2 countries.
Funding
Abstract
Previous studies have shown associations between genetic polymorphisms and pain tolerance, but psychological evaluations are seldom measured. The objective of this study was to determine the independent effects of demographic, psychological, and genetic predictors of cold noxious pain tolerance. Healthy subjects (n = 89) completed the Pain Catastrophizing Scale (PCS) and Fear of Pain Questionnaire (FPQ-III), underwent genotyping for candidate single nucleotide polymorphisms (SNPs), and completed a cold-pressor test in a 1-2°C water bath for a maximum of 3 minutes. The primary outcome measure was pain tolerance, defined as the maximum duration of time subjects left their nondominant hand in the cold-water bath. Cox proportional hazards regression indicated that female sex, Asian race, and increasing PCS and FPQ-III scores were associated with lower pain tolerance. No candidate SNP was significantly associated with pain tolerance. Future genetic studies should include demographic and psychological variables as confounders in experimental pain models.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.