Evidence map›Paper›PMID 30468029›Full record

ArticleKorean circulation journal2019

Assessment of the Clinical Heterogeneity of Kawasaki Disease Using Genetic Variants of

Bo Kyung Sim, Hyein Park, Jae Jung Kim, Sin Weon Yun, Jeong Jin Yu, Kyung Lim Yoon, Kyung Yil Lee, Hong Ryang Kil, Gi Beom Kim, Myung Ki Han and 8 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Korean circulation journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Antibodies and Immunity During Kawasaki Disease.Frontiers in cardiovascular medicine · 2020
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 10 institutions in 1 country.

Bo Kyung SimAsan Institute for Life Sciences, University of Ulsan College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0001-5928-4923
Hyein ParkAsan Institute for Life Sciences, University of Ulsan College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-4802-0137
Jae Jung KimAsan Institute for Life Sciences, University of Ulsan College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-7406-3261
Sin Weon YunDepartment of Pediatrics, Chung-Ang University Hospital, Seoul, Korea.ORCID https://orcid.org/0000-0001-8947-703X
Jeong Jin YuDepartment of Pediatrics, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0003-1601-3685
Kyung Lim YoonDepartment of Pediatrics, Kyung Hee University Hospital at Gangdong, Seoul, Korea.ORCID https://orcid.org/0000-0003-4734-900X
Kyung Yil LeeDepartment of Pediatrics, Daejeon St. Mary's Hospital, The Catholic University of Korea, Daejeon, Korea.ORCID https://orcid.org/0000-0001-6510-1580
Hong Ryang KilDepartment of Pediatrics, Chungnam National University Hospital, Daejeon, Korea.ORCID https://orcid.org/0000-0003-4925-8240
Gi Beom KimDepartment of Pediatrics, Seoul National University Children's Hospital, Seoul, Korea.ORCID https://orcid.org/0000-0002-7880-280X
Myung Ki HanDepartment of Pediatrics, Gangneung Asan Hospital, University of Ulsan College of Medicine, Gangneung, Korea.ORCID https://orcid.org/0000-0003-1817-8088
Min Seob SongDepartment of Pediatrics, Inje University Paik Hospital, Busan, Korea.ORCID https://orcid.org/0000-0003-3426-6803
Hyoung Doo LeeDepartment of Pediatrics, Pusan National University Hospital, Busan, Korea.ORCID https://orcid.org/0000-0002-6125-187X
Kee Soo HaDepartment of Pediatrics, Korea University Hospital, Seoul, Korea.ORCID https://orcid.org/0000-0001-6753-5411
Sejung SohnDepartment of Pediatrics, Ewha Womans University Medical Center, Seoul, Korea.ORCID https://orcid.org/0000-0001-9960-7774
Young Mi Hong *Department of Pediatrics, Ewha Womans University Medical Center, Seoul, Korea.ORCID https://orcid.org/0000-0002-6600-7876
Gi Young Jang *Department of Pediatrics, Korea University Hospital, Seoul, Korea.ORCID https://orcid.org/0000-0002-4831-1188
Jong Keuk Lee *Asan Institute for Life Sciences, University of Ulsan College of Medicine, Seoul, Korea. cookie_jklee@hotmail.com.ORCID https://orcid.org/0000-0003-1125-4017
Korean Kawasaki Disease Genetics Consortium
Ulsan College · KREwha Womans University Medical Center · KRKorea University Medical Center · KRChung-Ang University Hospital · KRChungnam National University Hospital · KRInje University Busan Paik Hospital · KRKyung Hee University Hospital at Gangdong · KRPusan National University Hospital · KRSeoul National University Children's Hospital · KRThe Catholic University of Korea Daejeon St. Mary's Hospital · KR

Funding

Korea Centers for Disease Control & Prevention 2014-ER7402-00Ministry of Health and Welfare HI15C1575
6 · The paper itself

Abstract

BACKGROUND AND

objectivesPatients with Kawasaki disease (KD) are clinically heterogeneous because its diagnosis is based solely on clinical observation and there are no definitive biomarkers. We dissected the clinical heterogeneity of KD patients using the KD-associated genetic variants.

methodsWe performed a genetic association analysis in several KD subgroups categorized by clinical characteristics using the KD-associated variants of the B lymphoid tyrosine kinase (

results

conclusionsKD is a clinically and genetically heterogeneous disease. These findings will provide new insights into the clinical and genetic heterogeneity of KD.

Indexed as

Genome-wide association studyMucocutaneous lymph node syndromePolymorphism, single nucleotide

Identifiers

PMID30468029
PMCPMC6331319
OpenAlexW2891526710

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.