ReviewBirth defects research2018
Uterine natural killer cells: To protect and to nurture.
Review in Birth defects research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed.
- The Impact of Endocrine Disruptor Exposure During Pregnancy on Bacterial Complications and Viral Infections: A Narrative Review.Microorganisms · 2026Review
- Changes in the Gut Microbiome and Pathologies in Pregnancy.International journal of environmental research and public health · 2022Review
- Role of Natural Killer Cells during Pregnancy and Related Complications.Biomolecules · 2022Review
- Proangiogenic actors: From the uterus to peripheral arterial disease?JVS-vascular science · 2022Article
- Ephrin-B2-expressing natural killer cells induce angiogenesis.JVS-vascular science · 2022Article
- Human-Induced CD49aFrontiers in immunology · 2022Article
- The Role of Uterine Natural Killer Cells on Recurrent Miscarriage and Recurrent Implantation Failure: From Pathophysiology to Treatment.Biomedicines · 2021Review
- Gut and Reproductive Tract Microbiota Adaptation during Pregnancy: New Insights for Pregnancy-Related Complications and Therapy.Microorganisms · 2021Review
- Beyond Uterine Natural Killer Cell Numbers in Unexplained Recurrent Pregnancy Loss: Combined Analysis of CD45, CD56, CD16, CD57, and CD138.Diagnostics (Basel, Switzerland) · 2020Article
- Review
- How I Manage Natural Killer Cell Deficiency.Journal of clinical immunology · 2020Article
- Collagen at the maternal-fetal interface in human pregnancy.International journal of biological sciences · 2020Review
- Molecules and Prostaglandins Related to Embryo Tolerance.Frontiers in immunology · 2020Review
- Uterine Natural Killer Cell Heterogeneity: Lessons From Mouse Models.Frontiers in immunology · 2020Review
- Single-cell technologies in reproductive immunology.American journal of reproductive immunology (New York, N.Y. : 1989) · 2019Review
- Transcriptional and Functional Programming of Decidual Innate Lymphoid Cells.Frontiers in immunology · 2019Article
- Uterine Natural Killer Cells.Frontiers in immunology · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
During the course of pregnancy, the maternal-fetal interface is tightly regulated and undergoes dynamic changes that promote the successful development of the semi-allogeneic fetus. In response to embryo implantation, the uterus remodels with maternal immune cells occupying the maternal-fetal interface and uterine natural killer (uNK) cells becoming the most prominent leukocyte. Recently, uNK cells have been discovered to be heterogeneous, including conventional NK and tissue-resident NK cells. Here, we will review the recent advances in uNK cell biology and discuss their functional mechanisms which protect and nurture the growing fetus.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.