Evidence map›Paper›PMID 30467830›Full record

ReviewClinical pharmacology and therapeutics2019

The Case for Pharmacogenetics-Guided Prescribing of Codeine in Children.

Roseann S Gammal, Kelly E Caudle, Charles T Quinn, Winfred C Wang, Andrea Gaedigk, Cynthia A Prows, Cyrine E Haidar, Annette K Taylor, Teri E Klein, Katrin Sangkuhl and 2 more

Open access · greenAbstract readReview
In one paragraph

Review in Clinical pharmacology and therapeutics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. The Perioperative Use of Codeine and Tramadol in Pediatric Population.Translational perioperative and pain medicine · 2025
    Article
  2. Review
  3. Implementation of CYP2D6-guided opioid therapy at Cincinnati Children's Hospital Medical Center.American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists · 2023
    Article
  4. Clinician adherence to pharmacogenomics prescribing recommendations in clinical decision support alerts.Journal of the American Medical Informatics Association : JAMIA · 2022
    Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Gene-Based Dose Optimization in Children.Annual review of pharmacology and toxicology · 2020
    Review
  10. Pharmacogenetics: Chasing Perfection.Clinical pharmacology and therapeutics · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 1 country.

Roseann S GammalPharmacy Practice, MCPHS University School of Pharmacy, Boston, Massachusetts, USA.
Kelly E CaudleDepartment of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Charles T QuinnPediatric Sickle Cell Program, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Winfred C WangDepartment of Hematology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Andrea GaedigkPharmacogenetics Core Laboratory, Children's Mercy Kansas City, Kansas City, Missouri, USA.
Cynthia A ProwsDivisions of Human Genetics and Patient Services, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Cyrine E HaidarDepartment of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Annette K TaylorMolecular Genetics, Colorado Coagulation, Laboratory Corporation of America Holdings, Englewood, Colorado, USA.
Teri E KleinDepartment of Biomedical Data Science, Stanford University, Stanford, California, USA.
Katrin SangkuhlDepartment of Biomedical Data Science, Stanford University, Stanford, California, USA.
Jane S HankinsDepartment of Hematology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Kristine R CrewsDepartment of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
St. Jude Children's Research Hospital · USCincinnati Children's Hospital Medical Center · USStanford University · USLabCorp (United States) · USMCPHS University · USMercy Research · US

Funding

PharmGKB: pharmacogenomics knowledge for precision medicineR24GM061374 · NIGMS · STANFORD UNIVERSITY · PI ALTMAN, RUSS BIAGIO, KLEIN, TERI ELLEN · 2010 to 2018
$25.2M
NIGMS NIH HHS R24 GM061374
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Analgesics, OpioidChildCodeineDrug PrescriptionsHumansPharmacogeneticsAnalgesics, OpioidCodeine

Identifiers

PMID30467830
PMCPMC8168366
OpenAlexW2900459753

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.