Evidence map›Paper›PMID 30467794›Full record

ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2019

Documentation and incidence of late effects and screening recommendations for adolescent and young adult head and neck cancer survivors treated with radiotherapy.

Sarah Nicole Hamilton, Omair Arshad, Jaime Kwok, Eric Tran, A Fuchsia Howard, Isabel Serrano, Karen Goddard

Abstract read
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In one paragraph

Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
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  4. The impact of survivorship care plans on adolescent and young adult head and neck cancer survivors and their primary care providers.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
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  6. Review
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  11. Impact of non-compliance with oral care on radiation caries in head and neck cancer survivors.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021
    Article
  12. Article
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  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sarah Nicole HamiltonBritish Columbia Cancer, Vancouver, BC, Canada. Shamilton7@bccancer.bc.ca.
Omair ArshadUniveristy of British Columbia, 600 W 10th Ave, Vancouver, BC, V5K 4E6, Canada.
Jaime KwokUniveristy of British Columbia, 600 W 10th Ave, Vancouver, BC, V5K 4E6, Canada.
Eric TranBritish Columbia Cancer, Vancouver, BC, Canada.
A Fuchsia HowardUniveristy of British Columbia, 600 W 10th Ave, Vancouver, BC, V5K 4E6, Canada.
Isabel SerranoBritish Columbia Cancer, Vancouver, BC, Canada.
Karen GoddardBritish Columbia Cancer, Vancouver, BC, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeA retrospective review of adolescent and young adult (AYA) head and neck cancer (HNC) patients treated with radiation therapy (RT) at British Columbia Cancer  was performed to determine the incidence of late toxicities, the documented late side effects discussed and the screening recommendations provided at the time of transfer of care to primary care providers (PCPs).

methodsCharts (n = 162) were reviewed for all patients 15 to 35 years at diagnosis with HNC treated with RT from 1960 to 2010 who survived > 5 years after diagnosis.

resultsA discussion regarding the risk of long-term side effects was documented in the initial consultation for 85% of patients. The majority of patients (78%) developed > 1 documented late effect. The most common were xerostomia (44%), skin changes (28%), neck fibrosis (22%), nasal crusting (16%), epistaxis (16%), and dental decay (14%). In all, 20% were currently followed or were followed until they died. Of the 80% transferred to their PCP, 14% had a formal discharge summary. For those discharged from British Columbia Cancer, documented recommendations included regular dental care (34%) and screening for hypothyroidism (5%) and second malignancy (4%).

conclusionsThe majority of AYA HNC patients treated with RT developed late side effects, and most PCPs were not sent a discharge summary outlining screening recommendations for delayed late effects. IMPLICATIONS FOR CANCER SURVIVORS: AYA HNC survivors treated with RT are at high risk for late effects and would benefit from a survivorship care plan outlining these risks and screening recommendations.

Indexed as

Cancer SurvivorsAdolescentBritish ColumbiaDental CariesDocumentationFemaleHead and Neck NeoplasmsHumansHypothyroidismIncidenceMaleMiddle AgedNeoplasms, Radiation-InducedNeoplasms, Second PrimaryRadiation InjuriesRadiotherapyAdolescent and young adultCancer survivorshipHead and neck cancerRadiation late effects

Identifiers

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.