Evidence map›Paper›PMID 30467646›Full record

ArticleInternational orthopaedics2019

Three-dimension-printed custom-made prosthetic reconstructions: from revision surgery to oncologic reconstructions.

Andrea Angelini, Giulia Trovarelli, Antonio Berizzi, Elisa Pala, Anna Breda, Pietro Ruggieri

Abstract read
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In one paragraph

Article in International orthopaedics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Health-related quality of life in patients with extremity bone sarcoma after surgical treatment: a systematic review.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024
    Pooled it
  3. Article
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  5. Article
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  7. Applications of 3D printing in orthopedics: a scoping review.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2025
    Article
  8. Review
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  10. Management of metastatic bone disease of the pelvis: current concepts.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2024
    Review
  11. Article
  12. Article
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  15. Point-of-Care Orthopedic Oncology Device Development.Current oncology (Toronto, Ont.) · 2023
    Article
  16. Article
  17. Custom designed and 3D-printed titanium pelvic implants for acetabular reconstruction after tumour resection.Hip international : the journal of clinical and experimental research on hip pathology and therapy · 2023
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  19. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Andrea AngeliniDepartment of Orthopedics and Orthopedic Oncology, University of Padova, Via Giustiniani, 235128, Padua, Italy.
Giulia TrovarelliDepartment of Orthopedics and Orthopedic Oncology, University of Padova, Via Giustiniani, 235128, Padua, Italy.
Antonio BerizziDepartment of Orthopedics and Orthopedic Oncology, University of Padova, Via Giustiniani, 235128, Padua, Italy.
Elisa PalaDepartment of Orthopedics and Orthopedic Oncology, University of Padova, Via Giustiniani, 235128, Padua, Italy.
Anna BredaDepartment of Orthopedics and Orthopedic Oncology, University of Padova, Via Giustiniani, 235128, Padua, Italy.
Pietro RuggieriDepartment of Orthopedics and Orthopedic Oncology, University of Padova, Via Giustiniani, 235128, Padua, Italy. pietro.ruggieri@unipd.it.ORCID http://orcid.org/0000-0001-9617-9882

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe use of custom-made 3D-printed prostheses for reconstruction of severe bone defects in selected cases is increasing. The aims of this study were to evaluate (1) the feasibility of surgical reconstruction with these prostheses in oncologic and non-oncologic settings and (2) the functional results, complications, and outcomes at short-term follow-up.

methodsWe analyzed 13 prospectively collected patients treated between June 2016 and January 2018. Diagnoses were primary bone tumour (7 patients), metastasis (3 patients), and revision of total hip arthroplasty (3 patients). Pelvis was the most frequent site of reconstruction (7 cases). Functional results were assessed with MSTS score and complications according to Henderson et al. Statistical analysis was performed using Kaplan-Meier and log-rank test curves.

resultsAt a mean follow-up of 13.7 months (range, 6-26 months), all patients except one were alive. Oncologic outcomes show seven patients NED (no evidence of disease), one NED after treatment of metastasis, one patient died of disease, and another one was alive with disease. Overall survival was 100% and 80% at one and two years, respectively. Seven complications occurred in five patients (38.5%). Survival to all complications was 62% at two years of follow-up. Functional outcome was good or excellent in all cases with a mean score of 80.3%.

conclusion3D-printed custom-made prostheses represent a promising reconstructive technique in musculoskeletal oncology and challenging revision surgery. Preliminary results were satisfactory. Further studies are needed to evaluate prosthetic design, fixation methods, and stability of the implants at long-term.

Indexed as

Arthroplasty, Replacement, HipPrinting, Three-DimensionalAdolescentAdultAgedBone DiseasesBone NeoplasmsBone ResorptionChildFeasibility StudiesFemaleHumansJoint DiseasesMaleMiddle AgedProsthesis Design3D-printed prosthesisBone tumourComplicationsComputer-aided designPelvic tumoursPelvisReconstruction

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.