Evidence map›Paper›PMID 30467596›Full record

ReviewWorld journal of urology2019

Diagnostic biomarkers in non-muscle invasive bladder cancer.

Izak Faiena, Charles J Rosser, Karim Chamie, Hideki Furuya

Abstract readReview
PubMed Publisher
In one paragraph

Review in World journal of urology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 31 citations in OpenAlex.

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  17. Urinary hyaluronic acid: a versatile marker of bladder cancer.International urology and nephrology · 2020
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Izak FaienaDepartment of Urology, Institute of Urologic Oncology, David Geffen School of Medicine at University of California, Los Angeles, Los Angeles, USA.
Charles J RosserClinical and Translational Research Program, University of Hawaii Cancer Center, 701 Ilalo Street Suite 353, Honolulu, HI, 96813, USA.
Karim ChamieDepartment of Urology, Institute of Urologic Oncology, David Geffen School of Medicine at University of California, Los Angeles, Los Angeles, USA.
Hideki FuruyaClinical and Translational Research Program, University of Hawaii Cancer Center, 701 Ilalo Street Suite 353, Honolulu, HI, 96813, USA. hfuruya@hawaii.edu.ORCID http://orcid.org/0000-0002-9536-8662
University of California, Los Angeles · USUniversity of Hawaiʻi at Mānoa · US

Funding

VALIDATION OF A MULTIPLEXED ASSAY FOR BLADDER CANCER DIAGNOSISR01CA198887 · NCI · UNIVERSITY OF HAWAII AT MANOA · PI ROSSER, CHARLES J · 2016 to 2025
$6.8M
6 · The paper itself

Abstract

Successful treatment of non-muscle invasive bladder cancer (NMIBC) relies heavily on our ability to accurately detect disease typically in the presence of hematuria as well as to detect the early recurrent tumors in patients with a history of NMIBC. Unfortunately, the current biomarker landscape for NMIBC is a work in progress. Cystoscopy continues to be the gold standard, but can still miss 10% of tumors. Therefore, physicians frequently use additional tools to aid in the diagnosis of bladder cancer, such as urinary cytology. The urinary cytology is a good option for high-grade disease; however, it is limited by low sensitivity in detecting low-grade disease, as well as variable interpretation among cytopathologists. Thus, the limitations of cystoscopy and urinary cytology have brought to light the need for more robust diagnostic assays. In this non-systematic review, we discuss the performance, potential advantages or disadvantages of these tests, and the future direction of biomarkers in NMIBC.

Indexed as

Biomarkers, TumorHumansNeoplasm InvasivenessUrinary Bladder NeoplasmsBiomarkers, TumorBiomarkersBladder cancerDiagnosisUrine

Identifiers

PMID30467596
OpenAlexW2901105640

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.