Evidence map›Paper›PMID 30467461›Full record

ArticleFrontiers in neuroscience2018

Behavioral Outcomes Following Brain-Computer Interface Intervention for Upper Extremity Rehabilitation in Stroke: A Randomized Controlled Trial.

Alexander B Remsik, Keith Dodd, Leroy Williams, Jaclyn Thoma, Tyler Jacobson, Janerra D Allen, Hemali Advani, Rosaleena Mohanty, Matt McMillan, Shruti Rajan and 15 more

Registry-linked trialAbstract read
In one paragraph

Article in Frontiers in neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02098265 (A Closed Loop Neural Activity Triggered Stroke Rehabilitation Device), which is not on this map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02098265 narecruitingnot on this map

A Closed Loop Neural Activity Triggered Stroke Rehabilitation Device

TypeinterventionalSponsorUniversity of Wisconsin, MadisonRan2010 to 2027Enrolled288ConditionsStrokeArmsFunctional Electric Stimulation (FES), Behavioral Assessments, Magnetic Resonance Imaging, EEG, RecoveriX
3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
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  5. Ketamine and Evolving Neuroplasticity.Clinical drug investigation · 2026
    Review
  6. Article
  7. EEG-based sensorimotor neurofeedback for motor neurorehabilitation in children and adults: A scoping review.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2024
    Article
  8. Article
  9. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors.

Alexander B RemsikDepartment of Radiology, University of Wisconsin - Madison, Madison, WI, United States.
Keith DoddDepartment of Radiology, University of Wisconsin - Madison, Madison, WI, United States.
Leroy WilliamsDepartment of Radiology, University of Wisconsin - Madison, Madison, WI, United States.
Jaclyn ThomaDepartment of Radiology, University of Wisconsin - Madison, Madison, WI, United States.
Tyler JacobsonDepartment of Radiology, University of Wisconsin - Madison, Madison, WI, United States.
Janerra D AllenDepartment of Radiology, University of Wisconsin - Madison, Madison, WI, United States.
Hemali AdvaniDepartment of Radiology, University of Wisconsin - Madison, Madison, WI, United States.
Rosaleena MohantyDepartment of Radiology, University of Wisconsin - Madison, Madison, WI, United States.
Matt McMillanDepartment of Radiology, University of Wisconsin - Madison, Madison, WI, United States.
Shruti RajanDepartment of Radiology, University of Wisconsin - Madison, Madison, WI, United States.
Matt WalczakDepartment of Radiology, University of Wisconsin - Madison, Madison, WI, United States.
Brittany M YoungDepartment of Radiology, University of Wisconsin - Madison, Madison, WI, United States.
Zack NigogosyanDepartment of Radiology, University of Wisconsin - Madison, Madison, WI, United States.
Cameron A RiveraDepartment of Radiology, University of Wisconsin - Madison, Madison, WI, United States.
Mohsen MazrooyisebdaniDepartment of Radiology, University of Wisconsin - Madison, Madison, WI, United States.
Neelima TellapragadaDepartment of Radiology, University of Wisconsin - Madison, Madison, WI, United States.
Leo M WaltonDepartment of Biomedical Engineering, University of Wisconsin - Madison, Madison, WI, United States.
Klevest GjiniDepartment of Radiology, University of Wisconsin - Madison, Madison, WI, United States.
Peter L E van KanDepartment of Kinesiology, University of Wisconsin - Madison, Madison, WI, United States.
Theresa J KangDepartment of Radiology, University of Wisconsin - Madison, Madison, WI, United States.
Justin A SattinNeuroscience Training Program, University of Wisconsin School of Medicine and Public Health, Madison, WI, United States.
Veena A NairDepartment of Radiology, University of Wisconsin - Madison, Madison, WI, United States.
Dorothy Farrar EdwardsDepartment of Kinesiology, University of Wisconsin - Madison, Madison, WI, United States.
Justin C WilliamsDepartment of Kinesiology, University of Wisconsin - Madison, Madison, WI, United States.
Vivek PrabhakaranDepartment of Radiology, University of Wisconsin - Madison, Madison, WI, United States.

Funding

Institutional Clinical and Translational Science AwardUL1TR000427 · NCATS · UNIVERSITY OF WISCONSIN-MADISON · PI DREZNER, MARC KENNETH · 2012 to 2016
$32.2M
INTEGRATED TRAINING FOR PHYSICIAN-SCIENTISTST32GM008692 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI BURKARD, MARK E · 1998 to 2020
$10.3M
GENERAL PURPOSE BRAIN-COMPUTER INTERFACE(BCI)SYSTEMR01EB000856 · NIBIB · WADSWORTH CENTER · PI SCHALK, GERWIN, WOLPAW, JONATHAN RICKEL · 2002 to 2012
$9.3M
Development of a Thin-Film MicroECOG Electrode for Chronic Cortical RecordingsR01EB009103 · NIBIB · WASHINGTON UNIVERSITY · PI MORAN, DANIEL WILLIAM, WILLIAMS, JUSTIN COLE · 2008 to 2011
$2.0M
Validating Resting State fMRI Derived Brain ConnectivityRC1MH090912 · NIMH · UNIVERSITY OF WISCONSIN-MADISON · PI MEYERAND, MARY E. · 2009 to 2010
$999k
Clinical Neuroengineering Training ProgramT32EB011434 · NIBIB · UNIVERSITY OF WISCONSIN-MADISON · PI MEYERAND, MARY E., PEARCE, ROBERT A · 2011 to 2015
$869k
Stroke PlasticityK23NS086852 · NINDS · UNIVERSITY OF WISCONSIN-MADISON · PI PRABHAKARAN, VIVEK · 2014 to 2017
$749k
NCATS NIH HHS UL1 TR000427NIBIB NIH HHS R01 EB000856NIBIB NIH HHS R01 EB009103NIBIB NIH HHS T32 EB011434NIGMS NIH HHS T32 GM008692NIMH NIH HHS RC1 MH090912NINDS NIH HHS K23 NS086852
6 · The paper itself

Abstract

Stroke is a leading cause of persistent upper extremity (UE) motor disability in adults. Brain-computer interface (BCI) intervention has demonstrated potential as a motor rehabilitation strategy for stroke survivors. This sub-analysis of ongoing clinical trial (NCT02098265) examines rehabilitative efficacy of this BCI design and seeks to identify stroke participant characteristics associated with behavioral improvement. Stroke participants (

Indexed as

brain–computer interface (BCI)hemiparesismotor functionrecoveryrehabilitationstrokeupper extremity

Identifiers

PMID30467461
PMCPMC6235950

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.