Evidence map›Paper›PMID 30467419›Full record

ArticleCellular & molecular immunology2020

Distinct editing functions of natural HLA-DM allotypes impact antigen presentation and CD4

Miguel Álvaro-Benito, Eliot Morrison, Friederike Ebner, Esam T Abualrous, Marie Urbicht, Marek Wieczorek, Christian Freund

Open access · bronzeAbstract read
In one paragraph

Article in Cellular & molecular immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 27 citations in OpenAlex.

  1. Genes · 2026
    Article
  2. Article
  3. Expression and Functional Characterization of Recombinant HLA-DM.Methods in molecular biology (Clifton, N.J.) · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. HLA Haplotypes and Relapse After Hematopoietic Cell Transplantation.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2024
    Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. CD4NPJ vaccines · 2020
    Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Miguel Álvaro-BenitoLaboratory of Protein Biochemistry, Department of Biology, Chemistry and Pharmacy, Freie Universität Berlin, Thielallee 63, 14195, Berlin, Germany. malvaro@zedat.fu-berlin.de.ORCID http://orcid.org/0000-0002-6019-3567
Eliot MorrisonLaboratory of Protein Biochemistry, Department of Biology, Chemistry and Pharmacy, Freie Universität Berlin, Thielallee 63, 14195, Berlin, Germany.
Friederike EbnerInstitut für Immunologie, Department of Veterinary Medicine, Freie Universität Berlin, Robert-von-Ostertag-Str. 7-13, 14163, Berlin, Germany.
Esam T AbualrousComputational Molecular Biology Group, Institute for Mathematics, Freie Universität Berlin, Berlin, Germany.
Marie UrbichtLaboratory of Protein Biochemistry, Department of Biology, Chemistry and Pharmacy, Freie Universität Berlin, Thielallee 63, 14195, Berlin, Germany.
Marek WieczorekLaboratory of Protein Biochemistry, Department of Biology, Chemistry and Pharmacy, Freie Universität Berlin, Thielallee 63, 14195, Berlin, Germany.
Christian FreundLaboratory of Protein Biochemistry, Department of Biology, Chemistry and Pharmacy, Freie Universität Berlin, Thielallee 63, 14195, Berlin, Germany. chfreund@zedat.fu-berlin.de.
Freie Universität Berlin · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Classical human leukocyte antigen (HLA) molecules of the major histocompatibility class II (MHCII) complex present peptides for the development, surveillance and activation of CD4

Indexed as

AllelesAntigen PresentationCD4-Positive T-LymphocytesDatabases, GeneticEpitopes, T-LymphocyteHaplotypesHEK293 CellsHLA-D AntigensHumansHydrogen-Ion ConcentrationLinkage DisequilibriumLymphocyte ActivationPeptidesPolymorphism, Single NucleotideProtein BindingProtein MultimerizationEpitopes, T-LymphocyteHLA-D AntigensHLA-DM antigensPeptidesProteomeEpitope selectionHLA-DM, Peptide editingImmunopeptidomeLimited polymorphismMHC class II

Identifiers

PMID30467419
PMCPMC7000412
OpenAlexW2900585717

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.