Evidence map›Paper›PMID 30467381›Full record

ArticleOncogene2019

Mutant Kras-induced upregulation of CD24 enhances prostate cancer stemness and bone metastasis.

Ching-Chieh Weng, Pei-Ya Ding, Yu-Hsuan Liu, John R Hawse, Malayannan Subramaniam, Chia-Chen Wu, Yu-Chun Lin, Chiao-Yun Chen, Wen-Chun Hung, Kuang-Hung Cheng

Open access · hybridAbstract read
In one paragraph

Article in Oncogene, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 49 citations in OpenAlex.

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  14. Macrophage heterogeneity in bone metastasis.Journal of bone oncology · 2024
    Article
  15. Article
  16. Amino Acid Metabolism in Bone Metastatic Disease.Current osteoporosis reports · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Ching-Chieh WengInstitute of Biomedical Sciences, National Sun Yat-Sen University, Kaohsiung, 804, Taiwan.
Pei-Ya DingInstitute of Biomedical Sciences, National Sun Yat-Sen University, Kaohsiung, 804, Taiwan.
Yu-Hsuan LiuInstitute of Biomedical Sciences, National Sun Yat-Sen University, Kaohsiung, 804, Taiwan.
John R HawseDepartment of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, MN, 55905, USA.
Malayannan SubramaniamDepartment of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, MN, 55905, USA.
Chia-Chen WuInstitute of Biomedical Sciences, National Sun Yat-Sen University, Kaohsiung, 804, Taiwan.
Yu-Chun LinInstitute of Biomedical Sciences, National Sun Yat-Sen University, Kaohsiung, 804, Taiwan.
Chiao-Yun ChenDepartment of Medical Imaging, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.
Wen-Chun HungNational Institute of Cancer Research, National Health Research Institutes, Tainan, Taiwan.
Kuang-Hung ChengInstitute of Biomedical Sciences, National Sun Yat-Sen University, Kaohsiung, 804, Taiwan. khcheng@faculty.nsysu.edu.tw.ORCID http://orcid.org/0000-0001-7427-4643
National Sun Yat-sen University · TWMayo Clinic · USKaohsiung Medical University · TWNational Health Research Institutes · TW

Funding

Kaohsiung Medical University (KMU) KMU-TP105G00Ministry of Science and Technology, Taiwan (Ministry of Science and Technology of Taiwan) 105-2321-B-400-010
6 · The paper itself

Abstract

Prostate cancer (PCA), one of the most common malignant tumors in men, is the second leading cause of cancer deaths in males worldwide. We report here that PCA models harboring conditional LSL/Kras

Indexed as

MutationAnimalsBone NeoplasmsCarcinogenesisCD24 AntigenCell MovementCell ProliferationCell ShapeGene Knockdown TechniquesHumansMaleMiceNeoplasm InvasivenessNeoplastic Stem CellsProstatic NeoplasmsProto-Oncogene Proteins p21(ras)CD24 AntigenKRAS protein, humanProto-Oncogene Proteins p21(ras)Tumor Suppressor Protein p53

Identifiers

PMID30467381
PMCPMC6484710
OpenAlexW2901134864

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.